Thrombophilia risk factors: Difference between revisions
Jump to navigation
Jump to search
m (→References) |
No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
The most common risk factors in the development of acquired thrombophlias are trauma, surgery, immobility, pregnancy, estrogen therapy, and age. The most common risk factors in the development of inherited thrombophilias are genetic mutations in factor V leiden and prothrombon G20210A. | |||
==Risk Factors== | ==Risk Factors== | ||
*The most common risk factors in the development of acquired thrombophlias are the following: | |||
* | **Trauma | ||
* | **Surgery | ||
* | **Immobility | ||
* | **Age | ||
* | **Hormones | ||
** | ***Pregnancy | ||
**[[Oral_contraceptive|Oral contraceptive pills]] | ***[[Oral_contraceptive|Oral contraceptive pills]] | ||
**[[Hormone_replacement_therapy|Hormone therapy]] | ***[[Hormone_replacement_therapy|Hormone therapy]] | ||
Common risk factors | Common risk factors for the development of inherited thrombophilias are a family history of thrombosis at an early age or a family history of inherited thrombophilia. | ||
Please see [[Thrombophilia classification|thrombophilia classification]] for a list conditions associated with acquired thrombophilias, and to the page on [[Thrombophilia_causes|causes of thrombophilia by organ system]] | Common genetic risk factors in the development of inherited thrombophilias are mutations in [[Factor V Leiden]] and [[Prothrombon G20210A]].<ref name="pmid24421360">{{cite journal| author=Cohoon KP, Heit JA| title=Inherited and secondary thrombophilia. | journal=Circulation | year= 2014 | volume= 129 | issue= 2 | pages= 254-7 | pmid=24421360 | doi=10.1161/CIRCULATIONAHA.113.001943 | pmc=3979345 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24421360 }} </ref><ref name="pmid11309638">{{cite journal| author=Seligsohn U, Lubetsky A| title=Genetic susceptibility to venous thrombosis. | journal=N Engl J Med | year= 2001 | volume= 344 | issue= 16 | pages= 1222-31 | pmid=11309638 | doi=10.1056/NEJM200104193441607 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11309638 }} </ref><ref name="pmid21340752">{{cite journal| author=Middeldorp S| title=Evidence-based approach to thrombophilia testing. | journal=J Thromb Thrombolysis | year= 2011 | volume= 31 | issue= 3 | pages= 275-81 | pmid=21340752 | doi=10.1007/s11239-011-0572-y | pmc=3056012 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21340752 }} </ref> | ||
Please see [[Thrombophilia classification|thrombophilia classification]] for a list conditions associated with acquired thrombophilias, and to the page on [[Thrombophilia_causes|causes of thrombophilia by organ system]]. | |||
==References== | ==References== | ||
| Line 25: | Line 28: | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 05:38, 21 July 2016
|
Thrombophilia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Thrombophilia risk factors On the Web |
|
American Roentgen Ray Society Images of Thrombophilia risk factors |
|
Risk calculators and risk factors for Thrombophilia risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Asiri Ediriwickrema, M.D., M.H.S. [2]
Overview
The most common risk factors in the development of acquired thrombophlias are trauma, surgery, immobility, pregnancy, estrogen therapy, and age. The most common risk factors in the development of inherited thrombophilias are genetic mutations in factor V leiden and prothrombon G20210A.
Risk Factors
- The most common risk factors in the development of acquired thrombophlias are the following:
- Trauma
- Surgery
- Immobility
- Age
- Hormones
- Pregnancy
- Oral contraceptive pills
- Hormone therapy
Common risk factors for the development of inherited thrombophilias are a family history of thrombosis at an early age or a family history of inherited thrombophilia.
Common genetic risk factors in the development of inherited thrombophilias are mutations in Factor V Leiden and Prothrombon G20210A.[1][2][3]
Please see thrombophilia classification for a list conditions associated with acquired thrombophilias, and to the page on causes of thrombophilia by organ system.
References
- ↑ Cohoon KP, Heit JA (2014). "Inherited and secondary thrombophilia". Circulation. 129 (2): 254–7. doi:10.1161/CIRCULATIONAHA.113.001943. PMC 3979345. PMID 24421360.
- ↑ Seligsohn U, Lubetsky A (2001). "Genetic susceptibility to venous thrombosis". N Engl J Med. 344 (16): 1222–31. doi:10.1056/NEJM200104193441607. PMID 11309638.
- ↑ Middeldorp S (2011). "Evidence-based approach to thrombophilia testing". J Thromb Thrombolysis. 31 (3): 275–81. doi:10.1007/s11239-011-0572-y. PMC 3056012. PMID 21340752.