Hypercalcemia natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Complications

Possible complications include:

Gastrointestinal:

• Pancreatitis
• Peptic ulcer disease

Kidney:

• Calcium deposits in the kidney (nephrocalcinosis)
• Dehydration
• High blood pressure
• Kidney failure
• Kidney stones

Psychological:

• Depression
• Difficulty concentrating or thinking

Skeletal:

• Bone cysts
• Fractures
• Osteoporosis

These complications of long-term hypercalcemia are uncommon today.