Drug induced liver injury medical therapy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Drug induced liver injury}} | {{Drug induced liver injury}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{rachita}} | ||
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==Overview== | ==Overview== | ||
The mainstay of therapy for drug induced liver injury is prompt withdrawal of the offending drug. | |||
==Medical Therapy== | ==Medical Therapy== | ||
It has been hypothesized that early drug withdrawal prevents progression to acute liver failure, but there is insufficient data to support this, as sometimes even a few days of exposure to a drug can cause a fatal outcome.<ref name="pmid24935270">{{cite journal| author=Chalasani NP, Hayashi PH, Bonkovsky HL, Navarro VJ, Lee WM, Fontana RJ et al.| title=ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury. | journal=Am J Gastroenterol | year= 2014 | volume= 109 | issue= 7 | pages= 950-66; quiz 967 | pmid=24935270 | doi=10.1038/ajg.2014.131 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24935270 }} </ref> | |||
==References== | ==References== | ||
Revision as of 23:39, 12 August 2016
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Drug induced liver injury Microchapters |
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Differentiating Drug Induced Liver Injury from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Drug Induced Liver Injury On the Web |
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American Roentgen Ray Society Images of Drug induced liver injury |
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Risk calculators and risk factors for Drug induced liver injury |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rachita Navara, M.D. [2]
Overview
The mainstay of therapy for drug induced liver injury is prompt withdrawal of the offending drug.
Medical Therapy
It has been hypothesized that early drug withdrawal prevents progression to acute liver failure, but there is insufficient data to support this, as sometimes even a few days of exposure to a drug can cause a fatal outcome.[1]
References
- ↑ Chalasani NP, Hayashi PH, Bonkovsky HL, Navarro VJ, Lee WM, Fontana RJ; et al. (2014). "ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury". Am J Gastroenterol. 109 (7): 950–66, quiz 967. doi:10.1038/ajg.2014.131. PMID 24935270.