Boil pathophysiology: Difference between revisions
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The microscopic features of furuncle are: | The microscopic features of furuncle are: | ||
*Infiltrate, predominantly consists of neutrophils with in the wall and ostia of hair follicle which later becomes more mixed with lymphocytes and macrophages creating a central focus of necrosis. | *Infiltrate, predominantly consists of neutrophils with in the wall and ostia of hair follicle which later becomes more mixed with lymphocytes and macrophages creating a central focus of necrosis. | ||
*Inflammation can either be | *Inflammation of hair follicle can either be: | ||
:*Superficial:limited to infandibulum | |||
:*Deep | |||
==References== | ==References== | ||
Revision as of 14:29, 8 August 2016
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Boil Microchapters |
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Boil pathophysiology On the Web |
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American Roentgen Ray Society Images of Boil pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Boil (furuncle) is the tender, deep, dome shaped skin infection of the hair follicle.
Pathophysiology
Folliculitis is the inflammation and infection of hair follicle.
Furuncle is a localized deep suppurative necrotizing form of folliculitis which involves dermis and subcutaneous tissue. Staphylococcus aureus is the most common causative agent. Following abrasion or cut the pathogen uses the entry site to invade and colonize the hair follicle leading to the formation of tender red perifollicular nodule which later becomes painful and fluctuant terminating in the discharge of pus and necrotic plug which may leave a scar.[1]
Furunculosis is the acute or chronic appearance of a number of furuncles at multiple skin sites. Recurrent furunculosis is defined as three or more attacks within 12 month period.[1] It is a contagious condition which usually develops in moist or sweaty areas such as scalp, face, buttocks, axillae and areas which are subject to friction and perspiration.
Group of furuncles coalesce to form carbuncle.
Associated Conditions
Gross Pathology
- A furuncle begins as a firm, tender, red, dome shaped nodule that soon becomes fluctuant (Pus filled) and painful.
- They are of varying size which can range from as small as a pea to as big as a golf ball.
Microscopic Pathology
The microscopic features of furuncle are:
- Infiltrate, predominantly consists of neutrophils with in the wall and ostia of hair follicle which later becomes more mixed with lymphocytes and macrophages creating a central focus of necrosis.
- Inflammation of hair follicle can either be:
- Superficial:limited to infandibulum
- Deep
References
- ↑ 1.0 1.1 Ibler KS, Kromann CB (2014). "Recurrent furunculosis - challenges and management: a review". Clin Cosmet Investig Dermatol. 7: 59–64. doi:10.2147/CCID.S35302. PMC 3934592. PMID 24591845.