Aphthous ulcer pathophysiology: Difference between revisions
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**[[Ulcerative colitis]] | **[[Ulcerative colitis]] | ||
**[[Human immunodeficiency virus]] infection | **[[Human immunodeficiency virus]] infection | ||
**[[Cyclic neutropenia]] | **[[Cyclic neutropenia]] | ||
*Microbial | *Microbial | ||
**Bacterial ([[streptococcus|streptococci]]) | **Bacterial ([[streptococcus|streptococci]]) | ||
**Viral ([[varicella zoster]] and [[cytomegalovirus]]) | **Viral ([[varicella zoster]] and [[cytomegalovirus]]) | ||
** [[Marshall syndrome]] | |||
*Genetics | *Genetics | ||
**Ethnicity | **Ethnicity | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{Oral pathology}} | |||
[[Category:Otolaryngology]] | [[Category:Otolaryngology]] |
Revision as of 13:33, 6 September 2016
Aphthous ulcer Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
The pathophysiology of Aphthous ulcers is not fully understood. It is though that reucurren
Pathophysiology
Pathogenesis
The exact pathogenesis of aphthous ulcer in not clear. Contributing factors include:
- Allergies
- Genetic predisposition
- Hormonal influences
- Hematologic abnormalities
- Immunologic factors
- Infectious agents
- Nutritional deficiencies
- Smoking cessation
- Stress
- Trauma
It is thought that aphthous ulcer is the result of the cross reactivity between Staphylococcus sanguis and 60kDa Heat shock protein (HSP60)
It is thought aphthous ulcer is a result of is caused by either , [hypothesis 2], or [hypothesis 3].
Associated conditions
- Systemic disease
- Microbial
- Bacterial (streptococci)
- Viral (varicella zoster and cytomegalovirus)
- Marshall syndrome
- Genetics
- Ethnicity
- Human leukocyte antigen haplotypes (HLA B51)
- Allergic/Immunologic
- Local T-lymphocyte cytotoxicity
- Sodium lauryl sulfate sensitivity (in tooth paste)
- Abnormal CD4/CD8 ratio
- Microbe-induced hypersensitivity
- Food sensitivity
- Others
- Antioxidants
- Non steroidal anti-inflammatory drugs (NSAIDs)
- Beta blockers
- Immunosuppressive drugs
- Stress
- Psychological imbalance