Erysipelas secondary prevention: Difference between revisions
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==Secondary Prevention== | ==Secondary Prevention== | ||
The mainstay of Erysipelas secondary prevention is prophylaxis. | The mainstay of Erysipelas secondary prevention is prophylaxis for severe cases with high frequency of recurrence. | ||
*[[Phenoxymethylpenicillin]] or [[erythromycin]] are indicated for prophylaxis for those with severe cases.<ref name="pmid3110071">{{cite journal |vauthors=Jorup-Rönström C, Britton S |title=Recurrent erysipelas: predisposing factors and costs of prophylaxis |journal=Infection |volume=15 |issue=2 |pages=105–6 |year=1987 |pmid=3110071 |doi= |url=}}</ref> | |||
*Research on the efficacy of [[antibiotic]] prophylaxis of Erysipelas is not conclusive for complete prevention of recurrence.<ref name="pmid17387234">{{cite journal |vauthors=Koster JB, Kullberg BJ, van der Meer JW |title=Recurrent erysipelas despite antibiotic prophylaxis: an analysis from case studies |journal=Neth J Med |volume=65 |issue=3 |pages=89–94 |year=2007 |pmid=17387234 |doi= |url=}}</ref> | |||
**[[Benzathine]] [[penicillin]], administered intravenously every 3 weeks for 6 months at 2.4 MU, prevented recurrence during treatment, but cessation of therapy resumed Erysipelas incidence for 25% of the patients.<ref name="pmid2861358">{{cite journal |vauthors=Duvanel T, Mérot Y, Harms M, Saurat JH |title=Prophylactic antibiotics in erysipelas |journal=Lancet |volume=1 |issue=8442 |pages=1401 |year=1985 |pmid=2861358 |doi= |url=}}</ref> | |||
**[[Erythromycin]] was shown to be effective prophylaxis throughout administration.<ref name="pmid3110071">{{cite journal |vauthors=Jorup-Rönström C, Britton S |title=Recurrent erysipelas: predisposing factors and costs of prophylaxis |journal=Infection |volume=15 |issue=2 |pages=105–6 |year=1987 |pmid=3110071 |doi= |url=}}</ref><ref name="pmid2002231">{{cite journal |vauthors=Kremer M, Zuckerman R, Avraham Z, Raz R |title=Long-term antimicrobial therapy in the prevention of recurrent soft-tissue infections |journal=J. Infect. |volume=22 |issue=1 |pages=37–40 |year=1991 |pmid=2002231 |doi= |url=}}</ref> | |||
**A randomized controlled trial of [[phenoxymethylpenicillin]] and [[erythromycin]] were shown to reduce Erysipelas recurrence in patients with [[venous insufficiency]] or lymphatic congestion, but relapse still occurred in 10% of the patients in the the treatment arm.<ref name="pmid8132369">{{cite journal |vauthors=Sjöblom AC, Eriksson B, Jorup-Rönström C, Karkkonen K, Lindqvist M |title=Antibiotic prophylaxis in recurrent erysipelas |journal=Infection |volume=21 |issue=6 |pages=390–3 |year=1993 |pmid=8132369 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
Revision as of 14:55, 16 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Secondary Prevention
The mainstay of Erysipelas secondary prevention is prophylaxis for severe cases with high frequency of recurrence.
- Phenoxymethylpenicillin or erythromycin are indicated for prophylaxis for those with severe cases.[1]
- Research on the efficacy of antibiotic prophylaxis of Erysipelas is not conclusive for complete prevention of recurrence.[2]
- Benzathine penicillin, administered intravenously every 3 weeks for 6 months at 2.4 MU, prevented recurrence during treatment, but cessation of therapy resumed Erysipelas incidence for 25% of the patients.[3]
- Erythromycin was shown to be effective prophylaxis throughout administration.[1][4]
- A randomized controlled trial of phenoxymethylpenicillin and erythromycin were shown to reduce Erysipelas recurrence in patients with venous insufficiency or lymphatic congestion, but relapse still occurred in 10% of the patients in the the treatment arm.[5]
References
- ↑ 1.0 1.1 Jorup-Rönström C, Britton S (1987). "Recurrent erysipelas: predisposing factors and costs of prophylaxis". Infection. 15 (2): 105–6. PMID 3110071.
- ↑ Koster JB, Kullberg BJ, van der Meer JW (2007). "Recurrent erysipelas despite antibiotic prophylaxis: an analysis from case studies". Neth J Med. 65 (3): 89–94. PMID 17387234.
- ↑ Duvanel T, Mérot Y, Harms M, Saurat JH (1985). "Prophylactic antibiotics in erysipelas". Lancet. 1 (8442): 1401. PMID 2861358.
- ↑ Kremer M, Zuckerman R, Avraham Z, Raz R (1991). "Long-term antimicrobial therapy in the prevention of recurrent soft-tissue infections". J. Infect. 22 (1): 37–40. PMID 2002231.
- ↑ Sjöblom AC, Eriksson B, Jorup-Rönström C, Karkkonen K, Lindqvist M (1993). "Antibiotic prophylaxis in recurrent erysipelas". Infection. 21 (6): 390–3. PMID 8132369.