Allergic colitis laboratory findings: Difference between revisions
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There are no specific diagnostic laboratory findings associated with allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination.<ref name="pmid20618740">{{cite journal| author=Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K et al.| title=World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines. | journal=Pediatr Allergy Immunol | year= 2010 | volume= 21 Suppl 21 | issue= | pages= 1-125 | pmid=20618740 | doi=10.1111/j.1399-3038.2010.01068.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20618740 }} </ref><ref name="pmid11264489">{{cite journal| author=Pumberger W, Pomberger G, Geissler W| title=Proctocolitis in breast fed infants: a contribution to differential diagnosis of haematochezia in early childhood. | journal=Postgrad Med J | year= 2001 | volume= 77 | issue= 906 | pages= 252-4 | pmid=11264489 | doi= | pmc=1741985 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11264489 }} </ref><ref name="pmid25976434">{{cite journal| author=Nowak-Węgrzyn A| title=Food protein-induced enterocolitis syndrome and allergic proctocolitis. | journal=Allergy Asthma Proc | year= 2015 | volume= 36 | issue= 3 | pages= 172-84 | pmid=25976434 | doi=10.2500/aap.2015.36.3811 | pmc=4405595 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25976434 }} </ref> | There are no specific diagnostic laboratory findings associated with allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination.<ref name="pmid20618740">{{cite journal| author=Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K et al.| title=World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines. | journal=Pediatr Allergy Immunol | year= 2010 | volume= 21 Suppl 21 | issue= | pages= 1-125 | pmid=20618740 | doi=10.1111/j.1399-3038.2010.01068.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20618740 }} </ref><ref name="pmid11264489">{{cite journal| author=Pumberger W, Pomberger G, Geissler W| title=Proctocolitis in breast fed infants: a contribution to differential diagnosis of haematochezia in early childhood. | journal=Postgrad Med J | year= 2001 | volume= 77 | issue= 906 | pages= 252-4 | pmid=11264489 | doi= | pmc=1741985 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11264489 }} </ref><ref name="pmid25976434">{{cite journal| author=Nowak-Węgrzyn A| title=Food protein-induced enterocolitis syndrome and allergic proctocolitis. | journal=Allergy Asthma Proc | year= 2015 | volume= 36 | issue= 3 | pages= 172-84 | pmid=25976434 | doi=10.2500/aap.2015.36.3811 | pmc=4405595 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25976434 }} </ref> | ||
===Stool microscopy=== | ===Stool microscopy=== | ||
May | *Presence of blood, either frank or occult blood | ||
*May show increased eosinophils which is suggestive of allergic colitis in the presence of typical clinical findings | |||
===Complete Blood Count with Differentials and Peripheral Blood Smear=== | ===Complete Blood Count with Differentials and Peripheral Blood Smear=== | ||
Revision as of 21:12, 20 September 2016
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Allergic colitis laboratory findings On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qasim Salau, M.B.B.S., FMCPaed [2]
Overview
There are no specific laboratory findings that are pathognomonic of allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination. Presence of eosinophils in the stool is suggestive of allergic colitis in the presence of typical clinical findings.[1][2][3]
Laboratory Findings
There are no specific diagnostic laboratory findings associated with allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination.[1][2][3]
Stool microscopy
- Presence of blood, either frank or occult blood
- May show increased eosinophils which is suggestive of allergic colitis in the presence of typical clinical findings
Complete Blood Count with Differentials and Peripheral Blood Smear
- A low hemoglobin or hematocrit with microcytosis or marginal normocytosis may be seen and indicative of iron deficiency anemia from blood loss
- Peripheral blood eosinophilia may rarely be seen especially in FPIES
- Elevated white blood cells with a left shift may be seen in severe acute FPIES
Iron studies
- Low ferritin with a high TIBC is suggestive of chronic blood loss by inflammatory bowel disease.
- High ferritin may be suggestive of anemia of chronic inflammatory conditions
Complete Metabolic Panel
- May show hypoalbuminemia especially in children with chronic FPIES
- Metabolic acidosis may be seen in FPIES
References
- ↑ 1.0 1.1 Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K; et al. (2010). "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines". Pediatr Allergy Immunol. 21 Suppl 21: 1–125. doi:10.1111/j.1399-3038.2010.01068.x. PMID 20618740.
- ↑ 2.0 2.1 Pumberger W, Pomberger G, Geissler W (2001). "Proctocolitis in breast fed infants: a contribution to differential diagnosis of haematochezia in early childhood". Postgrad Med J. 77 (906): 252–4. PMC 1741985. PMID 11264489.
- ↑ 3.0 3.1 Nowak-Węgrzyn A (2015). "Food protein-induced enterocolitis syndrome and allergic proctocolitis". Allergy Asthma Proc. 36 (3): 172–84. doi:10.2500/aap.2015.36.3811. PMC 4405595. PMID 25976434.