Sick sinus syndrome medical therapy: Difference between revisions

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==Overview==
==Overview==
The management of sick sinus syndrome depends on the underlying [[cause]] and the presenting [[symptoms]]. After correcting the reversible [[causes]] of sick sinus syndrome, it can be managed by placing an implantable pacemaker.
==Medical Therapy==
==Medical Therapy==
Bradyarrhythmias are well controlled with pacemakers, while tachyarrhythmias respond well to medical therapy. However, because both bradyarrhythmias and tachyarrhythmias may be present, drugs to control tachyarrhythmia may exacerbate bradyarrhythmia. Therefore, a pacemaker is implanted before drug therapy is begun for the tachyarrhythmia.
The management of sick sinus syndrome depends on the underlying [[cause]] and the presenting [[symptoms]]. After correcting the reversible [[causes]] of sick sinus syndrome, it can be managed by placing an implantable pacemaker.<ref name="pmid29261930">{{cite journal |vauthors=Dakkak W, Doukky R |title= |journal= |volume= |issue= |pages= |date= |pmid=29261930 |doi= |url=}}</ref>
 
*Clinical [[indications]] of the implantable pacemaker include:
In patients with bradyarrhythmias, there are no medications that can increase the heart rate and therefore will require pacemaker implantation. This will alleviate heart rates that are too slow or prolonged pauses in patients with SSS.<ref name="pmid14623796">{{cite journal| author=Gregoratos G| title=Cardiology patient pages. Sick sinus syndrome. | journal=Circulation | year= 2003 | volume= 108 | issue= 20 | pages= e143-4 | pmid=14623796 | doi=10.1161/01.CIR.0000102938.55119.EC | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14623796  }} </ref> In patients with bradycardia-tachycardia syndrome, pacemaker implantation with medications to slow the heart rate may be required. Persons suffering from SSS may have other conditions increasing their risk of stroke, such as atrial fibrillation, and should thus be treated with anticoagulants. <ref name="pmid14623796">{{cite journal| author=Gregoratos G| title=Cardiology patient pages. Sick sinus syndrome. | journal=Circulation | year= 2003 | volume= 108 | issue= 20 | pages= e143-4 | pmid=14623796 | doi=10.1161/01.CIR.0000102938.55119.EC | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14623796  }} </ref>
** [[Patients]] with documented bradycardia and are symptomaticĮ
 
** [[Patients]] with chronotropic incompetence
** Sinus node dysfunction secondary to medications necessitated by another medical condition
** [[Patients]] with heart rate < 40 per minute
===Contraindicated medications===
===Contraindicated medications===
{{MedCondContrAbs
{{MedCondContrAbs
|MedCond = Sick sinus syndrome|Adenosine|Carvedilol|Diltiazem|Dronedarone|Esmolol|Fingolimod|Metoprolol|Nebivolol|Propafenone|Verapamil}}
|MedCond = Sick sinus syndrome|Adenosine|Carvedilol|Diltiazem|Dronedarone|Esmolol|Fingolimod|Metoprolol|Nebivolol|Propafenone|Verapamil}}


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Electrophysiology]]
[[Category:Syndromes]]
[[Category:Cardiology]]
[[Category:Arrhythmia]]
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Revision as of 22:01, 8 April 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The management of sick sinus syndrome depends on the underlying cause and the presenting symptoms. After correcting the reversible causes of sick sinus syndrome, it can be managed by placing an implantable pacemaker.

Medical Therapy

The management of sick sinus syndrome depends on the underlying cause and the presenting symptoms. After correcting the reversible causes of sick sinus syndrome, it can be managed by placing an implantable pacemaker.[1]

  • Clinical indications of the implantable pacemaker include:
    • Patients with documented bradycardia and are symptomaticĮ
    • Patients with chronotropic incompetence
    • Sinus node dysfunction secondary to medications necessitated by another medical condition
    • Patients with heart rate < 40 per minute

Contraindicated medications

Sick sinus syndrome is considered an absolute contraindication to the use of the following medications:

References

  1. Dakkak W, Doukky R. PMID 29261930. Missing or empty |title= (help)

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