Statin therapy for ASCVD prevention: Difference between revisions
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The following is a treatment algorithm proposed by the AHA/ACC guidelines committee:<ref name="pmid24222016">{{cite journal| author=Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH et al.| title=2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. | journal=Circulation | year= 2014 | volume= 129 | issue= 25 Suppl 2 | pages= S1-S45 | pmid=24222016 | doi=10.1161/01.cir.0000437738.63853.7a | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24222016 }} </ref> | The following is a treatment algorithm proposed by the AHA/ACC guidelines committee:<ref name="pmid24222016">{{cite journal| author=Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH et al.| title=2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. | journal=Circulation | year= 2014 | volume= 129 | issue= 25 Suppl 2 | pages= S1-S45 | pmid=24222016 | doi=10.1161/01.cir.0000437738.63853.7a | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24222016 }} </ref> | ||
[[File:ACCAHA cholesterol treatment algorithm.jpg|900px]] | [[File:ACCAHA cholesterol treatment algorithm.jpg|900px]] | ||
Initial evaluation | |||
Initial evaluation prior to statin initiation include: | |||
*Fasting lipid panel | *Fasting lipid panel | ||
**Fasting lipid panel preferred. In a nonfasting individual, a non–HDL-C level !220 mg/dL could indicate genetic hypercholesterolemia that requires further evaluation or a secondary etiology. If nonfasting triglycerides are !500 mg/dL, a fasting lipid panel is required. | **Fasting lipid panel preferred. In a nonfasting individual, a non–HDL-C level !220 mg/dL could indicate genetic hypercholesterolemia that requires further evaluation or a secondary etiology. If nonfasting triglycerides are !500 mg/dL, a fasting lipid panel is required. | ||
| Line 12: | Line 14: | ||
*CK | *CK | ||
*Consider evaluation for other secondary causes | *Consider evaluation for other secondary causes | ||
==References== | ==References== | ||
Revision as of 21:17, 27 October 2016
Template:Hypercholesterolemia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Major Recommendations for Statin Therapy for ASCVD Prevention
The following is a treatment algorithm proposed by the AHA/ACC guidelines committee:[1]
Initial evaluation prior to statin initiation include:
- Fasting lipid panel
- Fasting lipid panel preferred. In a nonfasting individual, a non–HDL-C level !220 mg/dL could indicate genetic hypercholesterolemia that requires further evaluation or a secondary etiology. If nonfasting triglycerides are !500 mg/dL, a fasting lipid panel is required.
- ALT
- CK
- Consider evaluation for other secondary causes
References
- ↑ Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH; et al. (2014). "2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines". Circulation. 129 (25 Suppl 2): S1–S45. doi:10.1161/01.cir.0000437738.63853.7a. PMID 24222016.