Transient ischemic attack pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
== | ==Definition of Transient ischemic attack== | ||
According to American stroke association, transient ischemic stroke is defined as a transient episode of neurological dysfunction caused by a focal brain, spinal cord, or retinal ischaemia, without acute infarction.<ref name="pmid19423857">{{cite journal| author=Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E et al.| title=Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. | journal=Stroke | year= 2009 | volume= 40 | issue= 6 | pages= 2276-93 | pmid=19423857 | doi=10.1161/STROKEAHA.108.192218 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19423857 }} </ref> | |||
According to American stroke association, transient ischemic stroke is defined as a transient episode of neurological dysfunction caused by a focal brain, spinal cord, or retinal ischaemia, without acute infarction. | |||
==Pathophysiology== | ==Pathophysiology== | ||
The pathophysiologic mechanism of transient ischemic stroke may include temporary blockage of cerebral large or small blood vessel due to atherothrombotic or embolic cause followed by complete resolution of symptoms within few hours of onset. There may be mild tissue ischemia and hypoxia responsible for transitory symptomatology of patient. The specific clinical presentation of the patient correlates with the area of brain affected due to ischemia<ref name="pmid19423857">{{cite journal| author=Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E et al.| title=Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. | journal=Stroke | year= 2009 | volume= 40 | issue= 6 | pages= 2276-93 | pmid=19423857 | doi=10.1161/STROKEAHA.108.192218 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19423857 }} </ref><ref name="pmid: 1264882">{{cite journal| author=Caronna JJ| title=Transient ischemic attacks: Pathophysiology and medical management. | journal=Postgrad Med | year= 1976 | volume= 59 | issue= 3 | pages= 106-11 | pmid=: 1264882 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1264882 }} </ref> | |||
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Revision as of 21:23, 8 December 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Aysha Anwar, M.B.B.S[2]
Overview
Definition of Transient ischemic attack
According to American stroke association, transient ischemic stroke is defined as a transient episode of neurological dysfunction caused by a focal brain, spinal cord, or retinal ischaemia, without acute infarction.[1]
Pathophysiology
The pathophysiologic mechanism of transient ischemic stroke may include temporary blockage of cerebral large or small blood vessel due to atherothrombotic or embolic cause followed by complete resolution of symptoms within few hours of onset. There may be mild tissue ischemia and hypoxia responsible for transitory symptomatology of patient. The specific clinical presentation of the patient correlates with the area of brain affected due to ischemia[1][2]
References
- ↑ 1.0 1.1 Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E; et al. (2009). "Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists". Stroke. 40 (6): 2276–93. doi:10.1161/STROKEAHA.108.192218. PMID 19423857.
- ↑ Caronna JJ (1976). "Transient ischemic attacks: Pathophysiology and medical management". Postgrad Med. 59 (3): 106–11. PMID 1264882 : 1264882 Check
|pmid=
value (help).