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*'''Acute''': Acute osteomyelitis typically presents with gradual onset of symptoms over several days and less than 2 weeks.
*'''Acute''': Acute osteomyelitis typically presents with gradual onset of symptoms over several days and less than 2 weeks.
*'''Sub-acute''': Subacute hematogenous osteomyelitis has a more insidious onset and lacks the severity of symptoms, which makes the diagnosis of this disorder difficult. Typically, diagnosis is delayed for more than 2 weeks.
*'''Sub-acute''': Subacute hematogenous osteomyelitis has a more insidious onset and lacks the severity of symptoms, which makes the diagnosis of this disorder difficult. Typically, diagnosis is delayed for more than 2 weeks.
{|
! style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=3  | {{fontcolor|#FFFFFF|Sub-acute osteomyelitis}}
|
|
|-
|-style="background: #4479BA; color: #FFFFFF; text-align: center;"
! rowspan="1" colspan="1" |TYPE
! rowspan="1" colspan="1" |GLEDHILL CLASSIFICATION
! rowspan="1" colspan="1" |ROBERT ET AL. CLASSIFICATION
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|I}}
| style="padding: 5px 5px; background: #F5F5F5;" | Solitary localized zone of radiolucency surrounded<BR> by reactive new bone formation
| style="padding: 5px 5px; background: #F5F5F5;" | Ia—Punched-out radiolucency<BR>Ib—Punched-out radiolucent lesion with sclerotic margin
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|II}}
| style="padding: 5px 5px; background: #F5F5F5;" |Metaphyseal radiolucencies with cortical erosion
| style="padding: 5px 5px; background: #F5F5F5;" | --
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|III}}
| style="padding: 5px 5px; background: #F5F5F5;" | Cortical hyperostosis in diaphysis; no onion skin reaction
| style="padding: 5px 5px; background: #F5F5F5;" | Localized cortical periosteal reaction
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|IV}}
| style="padding: 5px 5px; background: #F5F5F5;" | Subperiosteal new bone and onion skin layering
| style="padding: 5px 5px; background: #F5F5F5;" | Onion skin periosteal reaction
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|V}}
| style="padding: 5px 5px; background: #F5F5F5;" | --
| style="padding: 5px 5px; background: #F5F5F5;" | Central radiolucency in epiphysis
|-
| style="background: #4479BA; padding: 5px 5px;" rowspan=1 colspan=1 |{{fontcolor|#FFFFFF|VI}}
| style="padding: 5px 5px; background: #F5F5F5;" | --
| style="padding: 5px 5px; background: #F5F5F5;" | Destructive process involving vertebral body
|-
|}





Revision as of 18:13, 23 December 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nate Michalak, B.A.

Overview

Two classification schemes are currently used. Lew and Waldvogel classify osteomyelitis according to duration and mechanism of infection: hematogenouos osteomyelitis, contiguous-focus osteomyelitis, and osteomyeltis secondary to vascular insufficiency. Cierny and Mader classify osteomyelitis according to anatomy of bone infection and host physiology. This systems classifies the location of infection into 4 stages and the host's physiology into 3 levels of compromise.

Classification

There are many types of classification schemes exist for osteomyelitis:

  • Lew and Waldvogel classify osteomyelitis according to duration and mechanism of infection (traditional classification)[1]
  • Cierny and Mader classify osteomyelitis according to anatomy of bone infection and host physiology[2]
  • The Cierny and Mader system offers a guide to treatment

Classification based on symptom chronology

  • Acute: Acute osteomyelitis typically presents with gradual onset of symptoms over several days and less than 2 weeks.
  • Sub-acute: Subacute hematogenous osteomyelitis has a more insidious onset and lacks the severity of symptoms, which makes the diagnosis of this disorder difficult. Typically, diagnosis is delayed for more than 2 weeks.


Sub-acute osteomyelitis
TYPE GLEDHILL CLASSIFICATION ROBERT ET AL. CLASSIFICATION
I Solitary localized zone of radiolucency surrounded
by reactive new bone formation
Ia—Punched-out radiolucency
Ib—Punched-out radiolucent lesion with sclerotic margin
II Metaphyseal radiolucencies with cortical erosion --
III Cortical hyperostosis in diaphysis; no onion skin reaction Localized cortical periosteal reaction
IV Subperiosteal new bone and onion skin layering Onion skin periosteal reaction
V -- Central radiolucency in epiphysis
VI -- Destructive process involving vertebral body




Lew and Waldvogel Etiologic System

Mechanism of Infection Description
Hematogenous Osteomyelitis Osteomyelitis develops after bacteremia
Contiguous-focus Osteomyelitis Direct inoculation of bone via trauma/fracture, surgery, prosthetic devices, or spread from soft tissue
Osteomyelitis Secondary to Vascular Insufficiency Reduced blood supply, usually in diabetic patients

Cierny and Mader Staging System

Classification Description
Anotomic Type Stage 1 Medullary osteomyeltitis: infection confined to the intramedullary bone surfaces
Stage 2 Superficial osteomyelitis: true contiguous infection (bone surface undergoes necrosis at the base of a soft tissue wound)
Stage 3 Localized osteomyelitis: full-thickness, cortical sequestration
Stage 4 Diffuse osteomyelitis: through-and-through process requiring intercalary reconstruction of bone
Physiological Class A Host Normal physiological, metabolic, and immunologic states
B Host Local compromise, systemic compromise, or both
C Host Morbidity of treatment is worse than disease

References

  1. Lew, Daniel P.; Waldvogel, Francis A. (1997). "Osteomyelitis". New England Journal of Medicine. 336 (14): 999–1007. doi:10.1056/NEJM199704033361406. ISSN 0028-4793.
  2. Mader, Jon T.; Shirtliff, Mark; Calhoun, Jason H. (1997). "Staging and Staging Application in Osteomyelitis". Clinical Infectious Diseases. 25 (6): 1303–1309. doi:10.1086/516149. ISSN 1058-4838.

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