Brucellosis history and symptoms: Difference between revisions
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|Acute brucellosis | |Acute brucellosis | ||
| | |Patients with Brucellosis, can present with diverse clinical presentation, which include systemic flu-like symptoms and symptoms to local infections:<ref>Colmenero JD, Reguera JM, Martos F, et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine (Baltimore) 1996; 75:195.</ref><ref>Mantur BG, Amarnath SK, Shinde RS. Review of clinical and laboratory features of human brucellosis. Indian J Med Microbiol 2007; 25:188.</ref><ref>Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med 2005; 352:2325.</ref><ref>Doganay M, Aygen B. Human brucellosis: An overview. Int J Infect Dis 2003; 7:173.</ref><ref>Young EJ. Brucellosis: current epidemiology, diagnosis, and management. Curr Clin Top Infect Dis 1995; 15:115.</ref><ref>Aygen B, Doganay M, Sumerkan B, et al. Clinical manifestations, complications and treatment of brucellosis: a retrospective evaluation of 480 patients. Med Malad Infect 2002; 32:485.</ref><ref>Geyik MF, Gür A, Nas K, et al. Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases. Swiss Med Wkly 2002; 132:98.</ref><ref>Mousa AM, Bahar RH, Araj GF, et al. Neurological complications of brucella spondylitis. Acta Neurol Scand 1990; 81:16.</ref><ref>Pappas G, Bosilkovski M, Akritidis N, et al. Brucellosis and the respiratory system. Clin Infect Dis 2003; 37:e95.</ref><ref>Herrick JA, Lederman RJ, Sullivan B, et al. Brucella arteritis: clinical manifestations, treatment, and prognosis. Lancet Infect Dis 2014; 14:520.</ref> | ||
Systemic symptoms | Systemic symptoms | ||
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* Pulmonary: Cough, chest pain, difficulty in breathing(pulmonary involvement present upto 7 percent of patients) | * Pulmonary: Cough, chest pain, difficulty in breathing(pulmonary involvement present upto 7 percent of patients) | ||
* Gastrointestinal: Abdominal pain and symptoms of [[hepatitis]] can be present in 3-6 percent of presenting patients | * Gastrointestinal: Abdominal pain and symptoms of [[hepatitis]] can be present in 3-6 percent of presenting patients | ||
* Neurological: Headache, confusion or altered sensorium(meningoencephalitits), loss of sensation(radiculopathies) can be present in 2-7 percent of patients | * Neurological: Headache, confusion or altered sensorium(meningoencephalitits), loss of sensation(radiculopathies or neuritis involving the cranial or peripheral nerves) can be present in 2-7 percent of patients | ||
* | * Cardiovascular: Chest pain is rare cardiovascular feature of brucellosis | ||
* Ocular: Difficulty in vision and Dimenision of vision | * Ocular: Difficulty in vision and Dimenision of vision | ||
* Dermatology: Rash, ulcer or tender swelling can present with brucellosis upto 10 percent of patient | * Dermatology: Rash, ulcer or tender swelling can present with brucellosis upto 10 percent of patient | ||
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|Presence of clinical manifestation for more then one year after established diagnosis of brucellosis is considered as chronic brucellosis. | |Presence of clinical manifestation for more then one year after established diagnosis of brucellosis is considered as chronic brucellosis. | ||
Clincial manifestations include: | Clincial manifestations include:<ref name="pmid7546364">{{cite journal| author=Young EJ| title=Brucellosis: current epidemiology, diagnosis, and management. | journal=Curr Clin Top Infect Dis | year= 1995 | volume= 15 | issue= | pages= 115-28 | pmid=7546364 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7546364 }}</ref> | ||
Uveitis: patients complains of difficulty of vision | Uveitis: patients complains of difficulty of vision |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Danitza Lukac
Overview
Symptoms of brucellosis include undulant fever, night sweats (with characteristic smell, likened to wet hay), and joint pain.[1]
Symptoms
Brucellosis | |
---|---|
Acute brucellosis | Patients with Brucellosis, can present with diverse clinical presentation, which include systemic flu-like symptoms and symptoms to local infections:[2][3][4][5][6][7][8][9][10][11]
Systemic symptoms
Focal organ wise symptoms:
|
Relapse |
Relapse occurs in 5 to 15 percent of patient usually in first 6 months following treatment, although in rare cases it may even occur in up to 12 months of treatment.[12][13] |
Chronic Brucellosis | Presence of clinical manifestation for more then one year after established diagnosis of brucellosis is considered as chronic brucellosis.
Clincial manifestations include:[14] Uveitis: patients complains of difficulty of vision Spondylitis, osteomyelitis, Arthralgias: patients complains of pain in joints or joint movement Intermittent sweating |
References
- ↑ Brucellosis. Wikipedia. https://en.wikipedia.org/wiki/Brucellosis. Accessed on February 4, 2016
- ↑ Colmenero JD, Reguera JM, Martos F, et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine (Baltimore) 1996; 75:195.
- ↑ Mantur BG, Amarnath SK, Shinde RS. Review of clinical and laboratory features of human brucellosis. Indian J Med Microbiol 2007; 25:188.
- ↑ Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med 2005; 352:2325.
- ↑ Doganay M, Aygen B. Human brucellosis: An overview. Int J Infect Dis 2003; 7:173.
- ↑ Young EJ. Brucellosis: current epidemiology, diagnosis, and management. Curr Clin Top Infect Dis 1995; 15:115.
- ↑ Aygen B, Doganay M, Sumerkan B, et al. Clinical manifestations, complications and treatment of brucellosis: a retrospective evaluation of 480 patients. Med Malad Infect 2002; 32:485.
- ↑ Geyik MF, Gür A, Nas K, et al. Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases. Swiss Med Wkly 2002; 132:98.
- ↑ Mousa AM, Bahar RH, Araj GF, et al. Neurological complications of brucella spondylitis. Acta Neurol Scand 1990; 81:16.
- ↑ Pappas G, Bosilkovski M, Akritidis N, et al. Brucellosis and the respiratory system. Clin Infect Dis 2003; 37:e95.
- ↑ Herrick JA, Lederman RJ, Sullivan B, et al. Brucella arteritis: clinical manifestations, treatment, and prognosis. Lancet Infect Dis 2014; 14:520.
- ↑ Ariza J, Bosilkovski M, Cascio A, et al. Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations. PLoS Med 2007; 4:e317.
- ↑ Ariza J, Corredoira J, Pallares R, et al. Characteristics of and risk factors for relapse of brucellosis in humans. Clin Infect Dis 1995; 20:1241.
- ↑ Young EJ (1995). "Brucellosis: current epidemiology, diagnosis, and management". Curr Clin Top Infect Dis. 15: 115–28. PMID 7546364.