Bacterial meningitis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
==Lab findings== | ==Lab findings== | ||
Labortary tests which may help identify the bacterial meningitis include non specific tests and specific diagnostic tests. | |||
===Non specific tests=== | |||
Non specific tests include blood tests such as complete blood count, liver function tests, renal function tests, biochemistry, and coagulation profile. | |||
{| style="border: 2px solid #DCDCDC; font-size: 90%; width: 30%;" | |||
|+ '''Laboratory findings''' | |||
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! style="width: 75px; background: #4479BA; text-align: center;"|{{fontcolor|#FFF|Test}} | |||
! style="width: 200px; background: #4479BA; text-align: center;"| {{fontcolor|#FFF|Findings}} | |||
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| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Complete blood count]]''' | |||
| style="background: #DCDCDC; padding: 5px;"| Decreased [[hemoglobin]]<br>Decreased [[hematocrit]]<br>Elevated [[CRP]]<ref name="pmid24754384">{{cite journal| author=Cooper EC, Ratnam I, Mohebbi M, Leder K| title=Laboratory features of common causes of fever in returned travelers. | journal=J Travel Med | year= 2014 | volume= 21 | issue= 4 | pages= 235-9 | pmid=24754384 | doi=10.1111/jtm.12122 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24754384 }} </ref> | |||
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| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[White blood cell count]]''' | |||
| style="background: #DCDCDC; padding: 5px;"| Elevated (children) or decreased [[leukocyte]] count (adults) | |||
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| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Biochemistry]]''' | |||
| style="background: #DCDCDC; padding: 5px;"| [[Hypoglycemia]]<br>Elevated [[creatinine]]<br>Elevated [[ALT]], [[AST]]<ref name="pmid6703825">{{cite journal| author=Klotz SA, Jorgensen JH, Buckwold FJ, Craven PC| title=Typhoid fever. An epidemic with remarkably few clinical signs and symptoms. | journal=Arch Intern Med | year= 1984 | volume= 144 | issue= 3 | pages= 533-7 | pmid=6703825 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6703825 }} </ref><ref name="pmid16274504">{{cite journal| author=Wang JL, Kao JH, Tseng SP, Teng LJ, Ho SW, Hsueh PR| title=Typhoid fever and typhoid hepatitis in Taiwan. | journal=Epidemiol Infect | year= 2005 | volume= 133 | issue= 6 | pages= 1073-9 | pmid=16274504 | doi=10.1017/S0950268805004048 | pmc=2870341 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16274504 }} </ref><br>Possible [[hyponatremia]]<br>Acidosis: High [[lactate]]; Low [[bicarbonate]] (shock) | |||
|- | |||
| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Coagulation]]''' | |||
| style="background: #DCDCDC; padding: 5px;"| [[Thrombocytopenia]]<ref name="pmid24754384">{{cite journal| author=Cooper EC, Ratnam I, Mohebbi M, Leder K| title=Laboratory features of common causes of fever in returned travelers. | journal=J Travel Med | year= 2014 | volume= 21 | issue= 4 | pages= 235-9 | pmid=24754384 | doi=10.1111/jtm.12122 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24754384 }} </ref> | |||
|- | |||
| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Urinalysis]]''' | |||
| style="background: #DCDCDC; padding: 5px;"| [[Proteinuria]]<br>[[hemoglobinuria]] (renal failure) | |||
|} | |||
===Specific tests=== | |||
Specific diagnostic tests include lumbar puncture with CSF examination and CSF culture. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 18:43, 9 January 2017
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Bacterial meningitis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
Lab findings
Labortary tests which may help identify the bacterial meningitis include non specific tests and specific diagnostic tests.
Non specific tests
Non specific tests include blood tests such as complete blood count, liver function tests, renal function tests, biochemistry, and coagulation profile.
| Test | Findings |
|---|---|
| Complete blood count | Decreased hemoglobin Decreased hematocrit Elevated CRP[1] |
| White blood cell count | Elevated (children) or decreased leukocyte count (adults) |
| Biochemistry | Hypoglycemia Elevated creatinine Elevated ALT, AST[2][3] Possible hyponatremia Acidosis: High lactate; Low bicarbonate (shock) |
| Coagulation | Thrombocytopenia[1] |
| Urinalysis | Proteinuria hemoglobinuria (renal failure) |
Specific tests
Specific diagnostic tests include lumbar puncture with CSF examination and CSF culture.
References
- ↑ 1.0 1.1 Cooper EC, Ratnam I, Mohebbi M, Leder K (2014). "Laboratory features of common causes of fever in returned travelers". J Travel Med. 21 (4): 235–9. doi:10.1111/jtm.12122. PMID 24754384.
- ↑ Klotz SA, Jorgensen JH, Buckwold FJ, Craven PC (1984). "Typhoid fever. An epidemic with remarkably few clinical signs and symptoms". Arch Intern Med. 144 (3): 533–7. PMID 6703825.
- ↑ Wang JL, Kao JH, Tseng SP, Teng LJ, Ho SW, Hsueh PR (2005). "Typhoid fever and typhoid hepatitis in Taiwan". Epidemiol Infect. 133 (6): 1073–9. doi:10.1017/S0950268805004048. PMC 2870341. PMID 16274504.