Brucellosis diagnostic criteria: Difference between revisions

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Revision as of 17:05, 6 January 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Danitza Lukac

Overview

There is no specific criteria for brucellosis, diagnosis is based on

The diagnosis of brucellosis is based on clinical and laboratory criteria.^[1]

Diagnostic Criteria

There is no specific diagnostic criteria for Brucellosis, Diagnosis is based on

History of potential exposure
Presentation consistent with the disease
Supporting laboratory findings

Diagnosis of brucellosis
History of potential exposure	Living or travelling to Brucellosis endemic countries Consuming unpasteurized dairy products or raw meat products Unsafe hunting practices Occupational risks such as slaughther house workers, meat-packing employees, and veterinarian
presentation consistent with the disease	An illness characterized by acute or insidious onset of fever and one or more of the following: Night sweats Arthralgia Headache Fatigue Anorexia Myalgia Weight loss Arthritis/spondylitis Meningitis Focal organ involvement (endocarditis, orchitis/epididymitis, hepatomegaly, splenomegaly)
Supporting laboratory findings	Definitive: Culture and identification of Brucella spp. from clinical specimens Evidence of a fourfold or greater rise in Brucella antibody titer between acute- and convalescent-phase serum specimens obtained greater than or equal to 2 weeks apart Presumptive: Brucella total antibody titer of greater than or equal to 160 by standard tube agglutination test (SAT) or Brucella microagglutination test (BMAT) in one or more serum specimens obtained after onset of symptoms Detection of Brucella DNA in a clinical specimen by PCR assay Other non-specific findings may include: Complete blood count: Normal or low with relative lymphocytosis. Low platelets may be reported Hemoglobin: Mild anemia is documented Normal or elevated ESR Normal or elevated C-reactive protein levels Raised fibrinogen degraded products

Reference

↑ Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016

[e-1] Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016

[1]

@@ Line 4: / Line 4: @@
 ==Overview==
+There is no specific criteria for brucellosis, diagnosis is based on
 The diagnosis of brucellosis is based on clinical and laboratory criteria.<ref name="e">Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016</ref>
 ==Diagnostic Criteria==
+There is no specific diagnostic criteria for Brucellosis, Diagnosis is based on
+* History of potential exposure
+* Presentation consistent with the disease
+* Supporting laboratory findings
 {| class="wikitable"
 ! colspan="2" |Diagnosis of brucellosis
@@ Line 12: / Line 18: @@
 |History of potential exposure
 |
+* Living or travelling to Brucellosis endemic countries
+* Consuming unpasteurized dairy products or raw meat products
+* Unsafe hunting practices
+* Occupational risks such as slaughther house workers, meat-packing employees, and veterinarian
 |-
 |presentation consistent with the disease
@@ Line 34: / Line 45: @@
 **[[Brucella|''Brucella'']] total antibody titer of greater than or equal to 160 by standard tube agglutination test (SAT) or [[Brucella|''Brucella'']] microagglutination test (BMAT) in one or more serum specimens obtained after onset of symptoms
 **Detection of [[Brucella|''Brucella'']] DNA in a clinical specimen by PCR assay
-|}
+Other non-specific findings may include:
-**
+* Complete blood count: Normal or low with relative lymphocytosis. Low platelets may be reported
+* Hemoglobin: Mild anemia is documented
-== '''Case Classification''' ==
+* Normal or elevated ESR
+* Normal or elevated C-reactive protein levels
-=== Probable ===
+* Raised fibrinogen  degraded products
-*A clinically compatible illness with at least one of the following:
+|}
-**Epidemiologically linked to a confirmed human or animal brucellosis case
-**Presumptive laboratory evidence, but without definitive laboratory evidence, of [[Brucella|''Brucella'']] infection
-=== Confirmed ===
-*A clinically compatible illness with definitive laboratory evidence of [[Brucella|''Brucella'']] infection
 ==Reference==
 {{reflist|2}}

Brucellosis diagnostic criteria: Difference between revisions

Revision as of 17:05, 6 January 2017

Overview

Diagnostic Criteria

Reference

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