Sandbox:peritonitis: Difference between revisions
Jump to navigation
Jump to search
| Line 22: | Line 22: | ||
=== Primary peritonitis === | === Primary peritonitis === | ||
As the primary disease (e.g. cirrhosis) progresses gram negative bacteria increase in numbers in the gut.<ref name="pmid9210626">Guarner C, Runyon BA, Young S, Heck M, Sheikh MY (1997) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=9210626 Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites.] ''J Hepatol'' 26 (6):1372-8. PMID: [https://pubmed.gov/9210626 9210626]</ref> Once bacteria reach a critical concentration in the gut lumen, they will translocate into the mesenteric lymphatic system because of the failure of the gut to contain bacteria and failure of the immune system to kill the virulent bacteria once they have escaped the gut. | As the primary disease (e.g. cirrhosis) progresses, gram negative bacteria increase in numbers in the gut.<ref name="pmid9210626">Guarner C, Runyon BA, Young S, Heck M, Sheikh MY (1997) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=9210626 Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites.] ''J Hepatol'' 26 (6):1372-8. PMID: [https://pubmed.gov/9210626 9210626]</ref> Once bacteria reach a critical concentration in the gut lumen, they will translocate into the mesenteric lymphatic system because of the failure of the gut to contain bacteria and failure of the immune system to kill the virulent bacteria once they have escaped the gut. | ||
== References == | == References == | ||
Revision as of 03:30, 6 January 2017
Definition
Peritonitis defined as the inflammation of the peritoneum from any cause.
Classification
Peritonitis is classified based on the etiology as follows:[1]
| Peritonitis | |||||||||||||||||||||||||||||||||||||||||
| Primary peritonitis | Secondary peritonitis | Tertiary peritonitis | |||||||||||||||||||||||||||||||||||||||
| ❑ Spontaneous peritonitis ❑ Peritonitis in patients with CAPD ❑ Tuberculous peritonitis | ❑ Peritonitis without evidence for pathogens ❑ Peritonitis with fungi ❑ Peritonitis with low-grade pathogenic bacteria | ||||||||||||||||||||||||||||||||||||||||
| Acute perforation peritonitis ❑ Gastrointestinal perforation ❑ Intestinal ischemia ❑ Pelviperitonitis and other forms | Postoperative peritonitis ❑ Anastomotic leak ❑ Accidental perforation and devascularization | Post-traumatic peritonitis ❑ After blunt abdominal trauma ❑ After penetrating abdominal trauma | |||||||||||||||||||||||||||||||||||||||
Pathogenesis
Peritonitis can be regarded as the localized event after any trigger of inflammation similar to the systemic inflammatory response(SIRS).[2]
Primary peritonitis
As the primary disease (e.g. cirrhosis) progresses, gram negative bacteria increase in numbers in the gut.[3] Once bacteria reach a critical concentration in the gut lumen, they will translocate into the mesenteric lymphatic system because of the failure of the gut to contain bacteria and failure of the immune system to kill the virulent bacteria once they have escaped the gut.
References
- ↑ Wittmann DH, Schein M, Condon RE (1996). "Management of secondary peritonitis". Ann Surg. 224 (1): 10–8. PMC 1235241. PMID 8678610.
- ↑ Marshall J, Sweeney D (1990) Microbial infection and the septic response in critical surgical illness. Sepsis, not infection, determines outcome. Arch Surg 125 (1):17-22; discussion 22-3. PMID: 2294878
- ↑ Guarner C, Runyon BA, Young S, Heck M, Sheikh MY (1997) Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites. J Hepatol 26 (6):1372-8. PMID: 9210626