Epiglottitis pathophysiology: Difference between revisions
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====Acute epiglottitis==== | ====Acute epiglottitis==== | ||
====Necrotizing epiglotitis==== | ====Necrotizing epiglotitis==== |
Revision as of 14:12, 11 January 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]
Overview
Pathophysiology
Pathogenesis
Acute epiglottitis
Necrotizing epiglotitis
The pathogeneiis of necrotizing epiglottitis involves the infection with CMV or EBV usually in immunocompromised people. Affected patients are usually neutropenic and lymphopenic at presentation. CMV and EBV modulate the host's immune defense facilitating immune evasion and thereby predisposing the patient to a superimposed infections. The causative organism of necrotizing epiglottitis is unclear.[1]
References
- ↑ Tebruegge M, Connell T, Kong K, Marks M, Curtis N (2009). "Necrotizing epiglottitis in an infant: an unusual first presentation of human immunodeficiency virus infection". Pediatr Infect Dis J. 28 (2): 164–6. doi:10.1097/INF.0b013e318187a869. PMID 19106777.