Cystitis secondary prevention: Difference between revisions
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:*Alternative regimen (3): [[Norfloxacin]] 400 mg PO bid in a single dose | :*Alternative regimen (3): [[Norfloxacin]] 400 mg PO bid in a single dose | ||
:*Alternative regimen (4): [[Gatifloxacin]] 200 mg PO qd in a single dose | :*Alternative regimen (4): [[Gatifloxacin]] 200 mg PO qd in a single dose | ||
*Post-Coital [[Ciprofloxacin]] has been found to be similar in effect to daily [[Ciprofloxacin]] | |||
*[[Nitrofurantoin]] and [[Fosfomycin]] effective for use as long term prophylaxis.<ref name="pmid9786476">{{cite journal| author=Brumfitt W, Hamilton-Miller JM| title=Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience. | journal=J Antimicrob Chemother | year= 1998 | volume= 42 | issue= 3 | pages= 363-71 | pmid=9786476 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9786476 }} </ref><ref name="pmid16080282">{{cite journal| author=Rudenko N, Dorofeyev A| title=Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study. | journal=Arzneimittelforschung | year= 2005 | volume= 55 | issue= 7 | pages= 420-7 | pmid=16080282 | doi=10.1055/s-0031-1296881 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16080282 }} </ref> | *[[Nitrofurantoin]] and [[Fosfomycin]] effective for use as long term prophylaxis.<ref name="pmid9786476">{{cite journal| author=Brumfitt W, Hamilton-Miller JM| title=Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience. | journal=J Antimicrob Chemother | year= 1998 | volume= 42 | issue= 3 | pages= 363-71 | pmid=9786476 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9786476 }} </ref><ref name="pmid16080282">{{cite journal| author=Rudenko N, Dorofeyev A| title=Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study. | journal=Arzneimittelforschung | year= 2005 | volume= 55 | issue= 7 | pages= 420-7 | pmid=16080282 | doi=10.1055/s-0031-1296881 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16080282 }} </ref> | ||
Revision as of 21:36, 13 January 2017
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Overview
Secondary prophylaxis of Cystitis is useful to prevent recurrent cystitis. It is more beneficial in patients in which Cystitis is associated with sexual intercourse, a structural defect or a disease like Diabetes that can lead to recurrent infections.
Secondary Prevention
The secondary Prevention of Cystitis includes the prophylaxis to prevent recurrent cystitis.
Antimicrobial Prophylaxis
- Prophylaxis is require din individuals having two or more episodes in 6 months or three or more episodes in 12 months period.[1][2]
- Prophylactic therapy using antimicrobial agents may be considered as either continuously or postcoital prophylaxis for 6 to 12 months.
- The following regimens may be used as single doses prior to sexual activity.[3]
- Prophylactic Therapy:
- Preferred regimen (1): Fosfomycin tromethamine 3 g PO in a single dose
- Preferred regimen (2): Nitrofurantoin monohydrate/macrocrystals 100 mg PO in a single dose
- Preferred regimen (3): Trimethoprim-Sulfamethoxazole 160/800 mg PO double-strength tablet bid in a single dose
- Preferred regimen (4): Trimethoprim 100 mg PO bid in a single dose
- Alternative regimen (1): Ciprofloxacin 250 mg PO bid in a single dose
- Alternative regimen (2): Levofloxacin 250 mg PO qd in a single dose
- Alternative regimen (3): Norfloxacin 400 mg PO bid in a single dose
- Alternative regimen (4): Gatifloxacin 200 mg PO qd in a single dose
- Post-Coital Ciprofloxacin has been found to be similar in effect to daily Ciprofloxacin
- Nitrofurantoin and Fosfomycin effective for use as long term prophylaxis.[4][5]
References
- ↑ Nicolle LE, Ronald AR (1987). "Recurrent urinary tract infection in adult women: diagnosis and treatment". Infect Dis Clin North Am. 1 (4): 793–806. PMID 3333659.
- ↑ Ronald AR, Conway B (1988). "An approach to urinary tract infections in ambulatory women". Curr Clin Top Infect Dis. 9: 76–125. PMID 3077293.
- ↑ Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG; et al. (2011). "International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases". Clin Infect Dis. 52 (5): e103–20. doi:10.1093/cid/ciq257. PMID 21292654.
- ↑ Brumfitt W, Hamilton-Miller JM (1998). "Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience". J Antimicrob Chemother. 42 (3): 363–71. PMID 9786476.
- ↑ Rudenko N, Dorofeyev A (2005). "Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study". Arzneimittelforschung. 55 (7): 420–7. doi:10.1055/s-0031-1296881. PMID 16080282.