Secondary peritonitis natural history: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
Factors affecting prognosis are: | |||
* Age | |||
* Blood pressure | |||
* Cause of infection | |||
* Site of origin of peritonitis | |||
* Number of organs involved in multi-organ-failure (MOF) | |||
* Pre-operative organ failure | |||
* Presence of metabolic acidosis | |||
* Serum albumin | |||
* New York Heart Association cardiac function status | |||
* Malnutrition | |||
* Malignoma | |||
* Fecal peritonitis | |||
==References== | ==References== |
Revision as of 22:57, 5 February 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]
Overview
Natural History
Secondary peritonitis is the initial phase of infection after intestinal perforation which can progress to abscess, if left untreated. Severe abdominal infections are invariably progress to a high level of sepsis, endotoxin production and systemic inflammatory response syndrome (SIRS), which often results in multiple organ failure.[1][2]
Complications
- Tertiary peritonitis usually follows operative attempts to treat secondary peritonitis and is almost always associated with a systemic inflammatory response. It is a persistent/recurrent infection with organisms of low virulence.
Prognosis
Factors affecting prognosis are:
- Age
- Blood pressure
- Cause of infection
- Site of origin of peritonitis
- Number of organs involved in multi-organ-failure (MOF)
- Pre-operative organ failure
- Presence of metabolic acidosis
- Serum albumin
- New York Heart Association cardiac function status
- Malnutrition
- Malignoma
- Fecal peritonitis
References
- ↑ Wong PF, Gilliam AD, Kumar S, Shenfine J, O'Dair GN, Leaper DJ (2005). "Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults". Cochrane Database Syst Rev (2): CD004539. doi:10.1002/14651858.CD004539.pub2. PMID 15846719.
- ↑ Berne TV, Yellin AW, Appleman MD, Heseltine PN (1982). "Antibiotic management of surgically treated gangrenous or perforated appendicitis. Comparison of gentamicin and clindamycin versus cefamandole versus cefoperazone". Am J Surg. 144 (1): 8–13. PMID 6211996.