Tropical sprue overview: Difference between revisions
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Exclusion of other diarrheal etiologies is required for the diagnosis of TS. | Exclusion of other diarrheal etiologies is required for the diagnosis of TS. | ||
===Diagnostic Criteria=== | ===Diagnostic Criteria=== | ||
Tropical sprue is a diagnosis of exclusion, it is usually considered in patients residing, or returning from a travel to endemic areas after staying for more than a week, manifesting with . Following signs may be indicative of TS: | |||
* Abnormal flattening of the [[villi]] and inflammation of the lining of the small intestine, observed during an [[endoscopy|endoscopic]] procedure. | |||
* Presence of inflammatory cells in the [[biopsy]] of small intestine tissue. | |||
* Low levels of vitamins [[vitamin A|A]], [[vitamin B12|B12]], [[vitamin E|E]], [[vitamin D|D]], and [[vitamin K|K]], as well as [[serum albumin]], [[calcium]], and [[folate]], revealed by a blood test. | |||
* Excess fat in the [[feces]] (steatorrhoea). | |||
===History and Symptoms=== | ===History and Symptoms=== | ||
Revision as of 19:03, 21 February 2017
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Tropical sprue Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Tropical sprue overview On the Web |
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American Roentgen Ray Society Images of Tropical sprue overview |
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Risk calculators and risk factors for Tropical sprue overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]
Synonyms and keywords: Chronic diarrhea, Intestinal malabsorption, Tropical malabsorption, Postinfective tropical malabsorption, Postinfective malabsorption, Tropical enteropathy, Tropical diarrhea, Military diarrhea, Cachectic diarrhea, Psilosis, Aphthae tropical, Chronic traveller's diarrhea, Tropical steatorrhea, Chronic malabsorption.
Overview
Tropical sprue is an acquired malabsorption disease of unknown etiology commonly found in the tropical regions, marked with abnormal flattening of the villi and inflammation of the lining of the small intestine. Ghoshal et al. defined a group of patients with TS by strict clinical and pathological criteria and show that aerobic bacteria contaminate the small bowel in patients with TS and that these patients have a prolonged orocecal transit time (OCTT) compared with healthy control subjects. It differs significantly from coeliac sprue.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Tropical sprue overview from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Exclusion of other diarrheal etiologies is required for the diagnosis of TS.
Diagnostic Criteria
Tropical sprue is a diagnosis of exclusion, it is usually considered in patients residing, or returning from a travel to endemic areas after staying for more than a week, manifesting with . Following signs may be indicative of TS:
- Abnormal flattening of the villi and inflammation of the lining of the small intestine, observed during an endoscopic procedure.
- Presence of inflammatory cells in the biopsy of small intestine tissue.
- Low levels of vitamins A, B12, E, D, and K, as well as serum albumin, calcium, and folate, revealed by a blood test.
- Excess fat in the feces (steatorrhoea).