Hypogonadism causes: Difference between revisions

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{{CMG}} {{AE}} {{ADI}} {{LRO}}
{{CMG}} {{AE}} {{ADI}} {{LRO}}
==Overview==
==Overview==
Hypogonadism is commonly caused by [[congenital]] and acquired [[genetic]] and [[endocrinology|endocrinological]] conditions. [[Malignant|Malignancies]] can be life threatening causes and should take priority when diagnosing the [[etiology]].
Hypogonadism is commonly caused by [[congenital]] and acquired [[genetic]] and [[endocrinology|endocrinological]] conditions. [[Malignant|Malignancies]] can be life threatening causes and should take priority when diagnosing the [[etiology]].<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref><ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>


==Causes<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>==
==Causes ==
<div style="-webkit-user-select: none;">
<div style="-webkit-user-select: none;">
===Life Threatening Causes===
===Life Threatening Causes===
*[[Astrocytoma]]
*[[Astrocytoma]]
*[[Chronic renal failure]]
*[[Chronic renal failure]]
*[[Papillary renal cell carcinoma ]]
*[[Renal cell carcinoma|Papillary renal cell carcinoma]] 
*[[Postinfectious lesions of the central nervous system (cns)]]
*Postinfectious lesions of the [[CNS|central nervous system (CNS)]]
*[[Ureter cancer ]]
*Ureter cancer 
*[[Urinary system cancer ]]
*Urinary system cancer 
*[[Wilms tumor ]]
*[[Wilms tumor ]]
*[[Infective endocarditis]]
*[[Infective endocarditis]]
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*[[Radiation therapy]]
*[[Radiation therapy]]
*[[Sertoli-cell]]-only syndrome
*[[Sertoli-cell]]-only syndrome
*Testicular biosynthetic defects
*[[Testicular]] biosynthetic defects
* Autoimmune oophoritis
* [[Autoimmune]] [[oophoritis]]
* Chemotherapy
* [[Chemotherapy]]
* Familial and sporadic XX gonadal dysgenesis and its variants
* Familial and sporadic XX gonadal [[dysgenesis]] and its variants
* Familial and sporadic XY gonadal dysgenesis and its variants
* Familial and sporadic XY gonadal dysgenesis and its variants
* [[FSH]] beta subunit mutation (follicle stimulating hormone)  
* [[FSH]] beta subunit mutation (follicle stimulating hormone)  
* [[FSH]] receptor mutation
* [[FSH]] receptor mutation
* Galactosemia
* [[Galactosemia]]
* Glycoprotein syndrome type 1
* [[Glycoprotein]] syndrome type 1
* LH (luteinizing hormone) beta subunit mutation
* LH (luteinizing hormone) beta subunit mutation
* LH/[[Ddx:Human Chorionic Gonadotropin|human chorionic gonadotropin]] resistance
* LH/[[Ddx:Human Chorionic Gonadotropin|human chorionic gonadotropin]] resistance
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* [[Polycystic ovarian disease]]
* [[Polycystic ovarian disease]]
* [[Radiation therapy]]
* [[Radiation therapy]]
* Resistant ovary  
* Resistant [[ovary]]
* [[Turner Syndrome]]
* [[Turner Syndrome]]
* [[Astrocytoma]]
* [[Astrocytoma]]
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* Congenital adrenal hypoplasia
* Congenital adrenal hypoplasia
* Congenital hypogonadotropic hypogonadism
* Congenital hypogonadotropic hypogonadism
* Craniofacial anomalies
* [[Craniofacial]] anomalies
* [[Craniopharyngioma]]
* [[Craniopharyngioma]]
* Exercise-induced amenorrhea
* Exercise-induced amenorrhea
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===Causes by Organ System===
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
{| style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Alström syndrome]],  [[Amyloidosis]],  [[Cardiofaciocutaneous syndrome]],  [[Vascular abnormalities of the cns]]
| style="width:75%" bgcolor="Beige" ; border="1" | [[Alström syndrome]],  [[Amyloidosis]],  [[Cardiofaciocutaneous syndrome]],  [[Vascular abnormalities of the cns]]
|-
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Alcohol]],  [[Alkylating agents]],  [[Cytotoxic therapeutic agents]],  [[Environmental toxins]],  [[Ethanol]],  [[Toxins]]
| bgcolor="Beige" | [[Alcohol]],  [[Alkylating agents]],  [[Cytotoxic therapeutic agents]],  [[Environmental toxins]],  [[Ethanol]],  [[Toxins]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| [[Jaffe-campanacci syndrome]],  [[Lepromatous leprosy]]
| bgcolor="Beige" | [[Jaffe-campanacci syndrome]],  [[Lepromatous leprosy]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Antiandrogens]],  [[Ketoconazole]],  [[Marijuana use]],  [[Opioids]]
| bgcolor="Beige" | [[Antiandrogens]],  [[Ketoconazole]],  [[Marijuana use]],  [[Opioids]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Adiposogenital dystrophy]],  [[Adrenal hypoplasia]],  [[Autoimmune polyendocrine syndrome type 2]],  [[Combined pituitary hormone deficiency ]],  [[Disorders of androgen synthesis]],  [[Functional gonadotropin deficiency]],  [[Glucocorticoids]],  [[Glycoprotein syndrome type 1]],  [[Gonadal dysgenesis ]],  [[Growth hormone secreting pituitary adenoma]],  [[Hyperprolactinemia]],  [[Hypogonadic hypogonadism]],  [[Hypopituitarism]],  [[Hypothalamic glioma]],  [[Panhypopituitarism]],  [[Pituitary tumor]],  [[Poems syndrome]],  [[Polycystic ovarian disease]],  [[Proprotein convertase 1/3 deficiency]],  [[Pseudohypoparathyroidism type 1a]],  [[Swyer's syndrome]],  [[Testicular biosynthetic defects]]
| bgcolor="Beige" | [[Adiposogenital dystrophy]],  [[Adrenal hypoplasia]],  [[Autoimmune polyendocrine syndrome type 2]],  [[Combined pituitary hormone deficiency ]] ,  [[Disorders of androgen synthesis]],  [[Functional gonadotropin deficiency]],  [[Glucocorticoids]],  [[Glycoprotein syndrome type 1]],  [[Gonadal dysgenesis ]] ,  [[Growth hormone secreting pituitary adenoma]],  [[Hyperprolactinemia]],  [[Hypogonadic hypogonadism]],  [[Hypopituitarism]],  [[Hypothalamic glioma]],  [[Panhypopituitarism]],  [[Pituitary tumor]],  [[Poems syndrome]],  [[Polycystic ovarian disease]],  [[Proprotein convertase 1/3 deficiency]],  [[Pseudohypoparathyroidism type 1a]],  [[Swyer's syndrome]],  [[Testicular biosynthetic defects]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Hepatic cirrhosis]]
| bgcolor="Beige" | [[Hepatic cirrhosis]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[17α-hydroxylase deficiency]],  [[17β-hydroxysteroid dehydrogenase iii deficiency]],  [[20-lyase deficiency]],  [[48, xxxy aneuploidy]],  [[48, xxyy aneuploidy]],  [[4h syndrome]],  [[Acrocephalopolysyndactyly type 2]],  [[Alström syndrome]],  [[Aromatase deficiency]],  [[Autoimmune oophoritis]],  [[Bardet-biedl syndrome]],  [[Belgian type mental retardation]],  [[Blepharophimosis syndrome]],  [[Borjeson-forssman-lehmann syndrome]],  [[Boucher-neuhäuser syndrome]],  [[Cardiofaciocutaneous syndrome]],  [[Ccfdn syndrome]],  [[Charge syndrome]],  [[Congenital adrenal hypoplasia]],  [[Craniofacial anomalies]],  [[Craniopharyngioma]],  [[Cryptorchidism]],  [[Didmoad syndrome]],  [[Dystrophia myotonica type 2]],  [[Fsh receptor deficiency]],  [[Fsh beta subunit mutation (follicle stimulating hormone)]],  [[Fsh receptor mutation]],  [[Galactose-1-phosphate uridyltransferase deficiency]],  [[Galactosemia]],  [[Gaucher disease]],  [[Gordon holmes syndrome]],  [[Hartsfield syndrome]],  [[Image syndrome]],  [[Isolated fsh deficiency]],  [[Isolated lh deficiency]],  [[Jaffe-campanacci syndrome]],  [[Kallmann syndrome]],  [[Klinefelter syndrome]],  [[Laurence-moon syndrome]],  [[Leptin deficiency]],  [[Lh (luteinizing hormone) beta subunit mutation]],  [[Lh receptor mutation]],  [[Lh resistance]],  [[Lipoid congenital adrenal hyperplasia]],  [[Malouf syndrome]],  [[Marinesco-sjogren-garland syndrome]],  [[Martsolf syndrome]],  [[Mobius syndrome]],  [[Mosaicism]],  [[Myotonic dystrophy]],  [[Noonan syndrome]],  [[Prader-willi syndrome]],  [[Proprotein convertase 1/3 deficiency]],  [[Resistant ovary]],  [[Rud syndrome]],  [[Sertoli-cell-only syndrome]],  [[Turner syndrome]],  [[Woodhouse-sakati syndrome]],  [[X-linked mental retardation-hypotonic facies syndrome]],  [[Xx gonadal dysgenesis]]
| bgcolor="Beige" | [[17α-hydroxylase deficiency]],  [[17β-hydroxysteroid dehydrogenase iii deficiency]],  [[20-lyase deficiency]],  [[48, xxxy aneuploidy]],  [[48, xxyy aneuploidy]],  [[4h syndrome]],  [[Acrocephalopolysyndactyly type 2]],  [[Alström syndrome]],  [[Aromatase deficiency]],  [[Autoimmune oophoritis]],  [[Bardet-biedl syndrome]],  [[Belgian type mental retardation]],  [[Blepharophimosis syndrome]],  [[Borjeson-forssman-lehmann syndrome]],  [[Boucher-neuhäuser syndrome]],  [[Cardiofaciocutaneous syndrome]],  [[Ccfdn syndrome]],  [[Charge syndrome]],  [[Congenital adrenal hypoplasia]],  [[Craniofacial anomalies]],  [[Craniopharyngioma]],  [[Cryptorchidism]],  [[Didmoad syndrome]],  [[Dystrophia myotonica type 2]],  [[Fsh receptor deficiency]],  [[Fsh beta subunit mutation (follicle stimulating hormone)]],  [[Fsh receptor mutation]],  [[Galactose-1-phosphate uridyltransferase deficiency]],  [[Galactosemia]],  [[Gaucher disease]],  [[Gordon holmes syndrome]],  [[Hartsfield syndrome]],  [[Image syndrome]],  [[Isolated fsh deficiency]],  [[Isolated lh deficiency]],  [[Jaffe-campanacci syndrome]],  [[Kallmann syndrome]],  [[Klinefelter syndrome]],  [[Laurence-moon syndrome]],  [[Leptin deficiency]],  [[Lh (luteinizing hormone) beta subunit mutation]],  [[Lh receptor mutation]],  [[Lh resistance]],  [[Lipoid congenital adrenal hyperplasia]],  [[Malouf syndrome]],  [[Marinesco-sjogren-garland syndrome]],  [[Martsolf syndrome]],  [[Mobius syndrome]],  [[Mosaicism]],  [[Myotonic dystrophy]],  [[Noonan syndrome]],  [[Prader-willi syndrome]],  [[Proprotein convertase 1/3 deficiency]],  [[Resistant ovary]],  [[Rud syndrome]],  [[Sertoli-cell-only syndrome]],  [[Turner syndrome]],  [[Woodhouse-sakati syndrome]],  [[X-linked mental retardation-hypotonic facies syndrome]],  [[Xx gonadal dysgenesis]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Glycoprotein syndrome type 1]],  [[Hemochromatosis]],  [[Langerhans histiocytosis]],  [[Leukoencephalopathy ]],  [[Zinc deficiency]]
| bgcolor="Beige" | [[Glycoprotein syndrome type 1]],  [[Hemochromatosis]],  [[Langerhans histiocytosis]],  [[Leukoencephalopathy ]] ,  [[Zinc deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| [[Chemotherapy]],  [[Opioids]],  [[Orchitis]],  [[Radiation therapy]],  [[Surgery]]
| bgcolor="Beige" | [[Chemotherapy]],  [[Opioids]],  [[Orchitis]],  [[Radiation therapy]],  [[Surgery]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[Aids]],  [[Infections]],  [[Mumps]]
| bgcolor="Beige" | [[Aids]],  [[Infections]],  [[Mumps]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| [[Astrocytoma]],  [[Belgian type mental retardation]],  [[Craniopharyngioma]],  [[Gordon holmes syndrome]],  [[Poems syndrome]],  [[Postinfectious lesions of the central nervous system (cns)]],  [[Vascular abnormalities of the cns]]
| bgcolor="Beige" | [[Astrocytoma]],  [[Belgian type mental retardation]],  [[Craniopharyngioma]],  [[Gordon holmes syndrome]],  [[Poems syndrome]],  [[Postinfectious lesions of the central nervous system (cns)]],  [[Vascular abnormalities of the cns]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Zinc deficiency]]
| bgcolor="Beige" | [[Zinc deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| [[Exercise-induced amenorrhea]],  [[Ovarian resistance syndrome]],  [[Ovarian torsion]],  [[Polycystic ovarian disease]],  [[Premature ovarian failure]],  [[Premature menopause]],  [[Resistant ovary]],  [[Rud syndrome]],  [[Suramin]],  [[Swyer's syndrome]]
| bgcolor="Beige" | [[Exercise-induced amenorrhea]],  [[Ovarian resistance syndrome]],  [[Ovarian torsion]],  [[Polycystic ovarian disease]],  [[Premature ovarian failure]],  [[Premature menopause]],  [[Resistant ovary]],  [[Rud syndrome]],  [[Suramin]],  [[Swyer's syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| [[Astrocytoma]],  [[Germinoma]],  [[Growth hormone secreting pituitary adenoma]],  [[Hypothalamic glioma]],  [[Langerhans histiocytosis]],  [[Optic glioma]],  [[Other germ cell tumors]],  [[Pituitary tumor]]
| bgcolor="Beige" | [[Astrocytoma]],  [[Germinoma]],  [[Growth hormone secreting pituitary adenoma]],  [[Hypothalamic glioma]],  [[Langerhans histiocytosis]],  [[Optic glioma]],  [[Other germ cell tumors]],  [[Pituitary tumor]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Optic glioma]]
| bgcolor="Beige" | [[Optic glioma]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Alcohol]]
| bgcolor="Beige" | [[Alcohol]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| [[Anorexia nervosa]]
| bgcolor="Beige" | [[Anorexia nervosa]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Chronic renal failure]],  [[Renal failure]]
| bgcolor="Beige" | [[Chronic renal failure]],  [[Renal failure]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Amyloidosis]],  [[Autoimmune damage]],  [[Autoimmunity]],  [[Chronic systemic illnesses]],  [[Lepromatous leprosy]]
| bgcolor="Beige" | [[Amyloidosis]],  [[Autoimmune damage]],  [[Autoimmunity]],  [[Chronic systemic illnesses]],  [[Lepromatous leprosy]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"| [[Aids]],  [[Epididymo-orchitis]],  [[Germinoma]],  [[Orchidectomy]],  [[Suramin]]
| bgcolor="Beige" | [[Aids]],  [[Epididymo-orchitis]],  [[Germinoma]],  [[Orchidectomy]],  [[Suramin]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| [[Head trauma]],  [[Hepatic cirrhosis]],  [[Ovarian torsion]],  [[Testicular torsion]],  [[Trauma]]
| bgcolor="Beige" | [[Head trauma]],  [[Hepatic cirrhosis]],  [[Ovarian torsion]],  [[Testicular torsion]],  [[Trauma]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| '''Urologic'''
|bgcolor="Beige"| [[Anorchia]],  [[Anorchidism]],  [[Congenital hypogonadotropic hypogonadism]],  [[Cryptorchidism]],  [[Disorders of androgen synthesis]],  [[Epididymo-orchitis]],  [[Gonadal dysgenesis ]],  [[Hypogonadic hypogonadism]],  [[Orchitis]],  [[Testicular torsion]],  [[Varicocele]]
| bgcolor="Beige" | [[Anorchia]],  [[Anorchidism]],  [[Congenital hypogonadotropic hypogonadism]],  [[Cryptorchidism]],  [[Disorders of androgen synthesis]],  [[Epididymo-orchitis]],  [[Gonadal dysgenesis ]] ,  [[Hypogonadic hypogonadism]],  [[Orchitis]],  [[Testicular torsion]],  [[Varicocele]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|}
|}
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{{WH}}
{{WH}}
{{WS}}
{{WS}}


[[Category:Endocrinology]]
[[Category:Endocrinology]]

Revision as of 15:21, 1 August 2017

Hypogonadism Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.

Overview

Hypogonadism is commonly caused by congenital and acquired genetic and endocrinological conditions. Malignancies can be life threatening causes and should take priority when diagnosing the etiology.[1][2]

Causes

Life Threatening Causes

Common Causes

Causes by Organ System

Cardiovascular Alström syndrome, Amyloidosis, Cardiofaciocutaneous syndrome, Vascular abnormalities of the cns
Chemical/Poisoning Alcohol, Alkylating agents, Cytotoxic therapeutic agents, Environmental toxins, Ethanol, Toxins
Dental Jaffe-campanacci syndrome, Lepromatous leprosy
Dermatologic No underlying causes
Drug Side Effect Antiandrogens, Ketoconazole, Marijuana use, Opioids
Ear Nose Throat No underlying causes
Endocrine Adiposogenital dystrophy, Adrenal hypoplasia, Autoimmune polyendocrine syndrome type 2, Combined pituitary hormone deficiency , Disorders of androgen synthesis, Functional gonadotropin deficiency, Glucocorticoids, Glycoprotein syndrome type 1, Gonadal dysgenesis , Growth hormone secreting pituitary adenoma, Hyperprolactinemia, Hypogonadic hypogonadism, Hypopituitarism, Hypothalamic glioma, Panhypopituitarism, Pituitary tumor, Poems syndrome, Polycystic ovarian disease, Proprotein convertase 1/3 deficiency, Pseudohypoparathyroidism type 1a, Swyer's syndrome, Testicular biosynthetic defects
Environmental No underlying causes
Gastroenterologic Hepatic cirrhosis
Genetic 17α-hydroxylase deficiency, 17β-hydroxysteroid dehydrogenase iii deficiency, 20-lyase deficiency, 48, xxxy aneuploidy, 48, xxyy aneuploidy, 4h syndrome, Acrocephalopolysyndactyly type 2, Alström syndrome, Aromatase deficiency, Autoimmune oophoritis, Bardet-biedl syndrome, Belgian type mental retardation, Blepharophimosis syndrome, Borjeson-forssman-lehmann syndrome, Boucher-neuhäuser syndrome, Cardiofaciocutaneous syndrome, Ccfdn syndrome, Charge syndrome, Congenital adrenal hypoplasia, Craniofacial anomalies, Craniopharyngioma, Cryptorchidism, Didmoad syndrome, Dystrophia myotonica type 2, Fsh receptor deficiency, Fsh beta subunit mutation (follicle stimulating hormone), Fsh receptor mutation, Galactose-1-phosphate uridyltransferase deficiency, Galactosemia, Gaucher disease, Gordon holmes syndrome, Hartsfield syndrome, Image syndrome, Isolated fsh deficiency, Isolated lh deficiency, Jaffe-campanacci syndrome, Kallmann syndrome, Klinefelter syndrome, Laurence-moon syndrome, Leptin deficiency, Lh (luteinizing hormone) beta subunit mutation, Lh receptor mutation, Lh resistance, Lipoid congenital adrenal hyperplasia, Malouf syndrome, Marinesco-sjogren-garland syndrome, Martsolf syndrome, Mobius syndrome, Mosaicism, Myotonic dystrophy, Noonan syndrome, Prader-willi syndrome, Proprotein convertase 1/3 deficiency, Resistant ovary, Rud syndrome, Sertoli-cell-only syndrome, Turner syndrome, Woodhouse-sakati syndrome, X-linked mental retardation-hypotonic facies syndrome, Xx gonadal dysgenesis
Hematologic Glycoprotein syndrome type 1, Hemochromatosis, Langerhans histiocytosis, Leukoencephalopathy , Zinc deficiency
Iatrogenic Chemotherapy, Opioids, Orchitis, Radiation therapy, Surgery
Infectious Disease Aids, Infections, Mumps
Musculoskeletal/Orthopedic No underlying causes
Neurologic Astrocytoma, Belgian type mental retardation, Craniopharyngioma, Gordon holmes syndrome, Poems syndrome, Postinfectious lesions of the central nervous system (cns), Vascular abnormalities of the cns
Nutritional/Metabolic Zinc deficiency
Obstetric/Gynecologic Exercise-induced amenorrhea, Ovarian resistance syndrome, Ovarian torsion, Polycystic ovarian disease, Premature ovarian failure, Premature menopause, Resistant ovary, Rud syndrome, Suramin, Swyer's syndrome
Oncologic Astrocytoma, Germinoma, Growth hormone secreting pituitary adenoma, Hypothalamic glioma, Langerhans histiocytosis, Optic glioma, Other germ cell tumors, Pituitary tumor
Ophthalmologic Optic glioma
Overdose/Toxicity Alcohol
Psychiatric Anorexia nervosa
Pulmonary No underlying causes
Renal/Electrolyte Chronic renal failure, Renal failure
Rheumatology/Immunology/Allergy Amyloidosis, Autoimmune damage, Autoimmunity, Chronic systemic illnesses, Lepromatous leprosy
Sexual Aids, Epididymo-orchitis, Germinoma, Orchidectomy, Suramin
Trauma Head trauma, Hepatic cirrhosis, Ovarian torsion, Testicular torsion, Trauma
Urologic Anorchia, Anorchidism, Congenital hypogonadotropic hypogonadism, Cryptorchidism, Disorders of androgen synthesis, Epididymo-orchitis, Gonadal dysgenesis , Hypogonadic hypogonadism, Orchitis, Testicular torsion, Varicocele
Miscellaneous No underlying causes

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

  1. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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