Pyogenic liver abscess laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Diagnostic Criteria

Diagnostic criteria for pyogenic liver abscess are:

• Liver aspirate or surgical tissue culture positive from a discrete liver abscess
• Diagnostic imaging consistent with liver abscess with a concurrent positive blood culture
• Diagnostic imaging consistent with liver abscess and a defined radiologic and clinical response to antimicrobial management even if cultures were negative or not performed.

Laboratory findings

• Laboratory tests consistent with diagnosis of amoebic liver abscess include:

Lab Test	Findings
Complete Blood Picture	Hemoglobin <10g/dl Leukocytosis Neutrophilia
ESR and CRP	Elevated ESR and C reactive protein
Liver function tests	Elevated alkaline phosphatase Elevated serum aspartate aminotransferase Elevated serum alanine transferase Elevated bilurubin Decreased albumin and increased globulin
Blood culture