Histoplasmosis pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Transmission=== | ===Transmission=== | ||
*Histoplasmosis is typically acquired via inhalation of airborne microconidia, often after disturbance of contaminated material. | *Histoplasmosis is typically acquired via inhalation of airborne microconidia, often after disturbance of contaminated material.<ref name="pmid22092757">{{cite journal| author=Edwards JA, Rappleye CA| title=Histoplasma mechanisms of pathogenesis--one portfolio doesn't fit all. | journal=FEMS Microbiol Lett | year= 2011 | volume= 324 | issue= 1 | pages= 1-9 | pmid=22092757 | doi=10.1111/j.1574-6968.2011.02363.x | pmc=3228276 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22092757 }} </ref> | ||
*Primary cutaneous histoplasmosis and solid organ donor-derived histoplasmosis have been observed although extremely uncommon.<ref name=cdc3>Information for Healthcare Professionals about Histoplasmosis. Centers for Disease Control and Prevention. 2015. Available at: http://www.cdc.gov/fungal/diseases/histoplasmosis/health-professionals.html. Accessed February 2, 2016.</ref> | *Primary cutaneous histoplasmosis and solid organ donor-derived histoplasmosis have been observed although extremely uncommon.<ref name=cdc3>Information for Healthcare Professionals about Histoplasmosis. Centers for Disease Control and Prevention. 2015. Available at: http://www.cdc.gov/fungal/diseases/histoplasmosis/health-professionals.html. Accessed February 2, 2016.</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Transmission
- Histoplasmosis is typically acquired via inhalation of airborne microconidia, often after disturbance of contaminated material.[1]
- Primary cutaneous histoplasmosis and solid organ donor-derived histoplasmosis have been observed although extremely uncommon.[2]
Gross pathology
Microscopic pathology
References
- ↑ Edwards JA, Rappleye CA (2011). "Histoplasma mechanisms of pathogenesis--one portfolio doesn't fit all". FEMS Microbiol Lett. 324 (1): 1–9. doi:10.1111/j.1574-6968.2011.02363.x. PMC 3228276. PMID 22092757.
- ↑ Information for Healthcare Professionals about Histoplasmosis. Centers for Disease Control and Prevention. 2015. Available at: http://www.cdc.gov/fungal/diseases/histoplasmosis/health-professionals.html. Accessed February 2, 2016.