Fibroadenoma differential diagnosis: Difference between revisions
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Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as phyllodes tumor, hamartoma, and adenomyoepithelioma.><ref name="patho">Fibroadenoma. Libre Pathology (2015) http://librepathology.org/wiki/index.php/Fibroadenoma Accessed on January, 29 2016</ref><ref name="patho2">Breast-nonmalignant-Fibroadenoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/breastfibroadenoma.html Accessed on January, 29 2016</ref> | Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as phyllodes tumor, hamartoma, and adenomyoepithelioma.><ref name="patho">Fibroadenoma. Libre Pathology (2015) http://librepathology.org/wiki/index.php/Fibroadenoma Accessed on January, 29 2016</ref><ref name="patho2">Breast-nonmalignant-Fibroadenoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/breastfibroadenoma.html Accessed on January, 29 2016</ref> | ||
==Differentiating Fibroadenoma from other Diseases== | ==Differentiating Fibroadenoma from other Diseases== | ||
Fibroadenoma must be differentiated from other diseases that cause [[breast pain]] and [[swelling]] as shown below:<ref name="pmid16713771">{{cite journal| author=Greydanus DE, Matytsina L, Gains M| title=Breast disorders in children and adolescents. | journal=Prim Care | year= 2006 | volume= 33 | issue= 2 | pages= 455-502 | pmid=16713771 | doi=10.1016/j.pop.2006.02.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16713771 }} </ref><ref name="pmid23450563">{{cite journal| author=Jahanfar S, Ng CJ, Teng CL| title=Antibiotics for mastitis in breastfeeding women. | journal=Cochrane Database Syst Rev | year= 2013 | volume= | issue= 2 | pages= CD005458 | pmid=23450563 | doi=10.1002/14651858.CD005458.pub3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23450563 }} </ref> <ref name="pmid24791941">{{cite journal| author=Lam E, Chan T, Wiseman SM| title=Breast abscess: evidence based management recommendations. | journal=Expert Rev Anti Infect Ther | year= 2014 | volume= 12 | issue= 7 | pages= 753-62 | pmid=24791941 | doi=10.1586/14787210.2014.913982 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24791941 }} </ref><ref name="pmid11250736">{{cite journal| author=Kleer CG, van Golen KL, Merajver SD| title=Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants. | journal=Breast Cancer Res | year= 2000 | volume= 2 | issue= 6 | pages= 423-9 | pmid=11250736 | doi=10.1186/bcr89 | pmc=138665 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11250736 }} </ref><ref name="pmid20603440">{{cite journal| author=Dawood S, Merajver SD, Viens P, Vermeulen PB, Swain SM, Buchholz TA et al.| title=International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment. | journal=Ann Oncol | year= 2011 | volume= 22 | issue= 3 | pages= 515-23 | pmid=20603440 | doi=10.1093/annonc/mdq345 | pmc=3105293 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20603440 }} </ref><ref name="pmid1588366">{{cite journal| author=Jaiyesimi IA, Buzdar AU, Hortobagyi G| title=Inflammatory breast cancer: a review. | journal=J Clin Oncol | year= 1992 | volume= 10 | issue= 6 | pages= 1014-24 | pmid=1588366 | doi=10.1200/JCO.1992.10.6.1014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1588366 }} </ref><ref name="pmid17126205">{{cite journal| author=Indelicato DJ, Grobmyer SR, Newlin H, Morris CG, Haigh LS, Copeland EM et al.| title=Delayed breast cellulitis: an evolving complication of breast conservation. | journal=Int J Radiat Oncol Biol Phys | year= 2006 | volume= 66 | issue= 5 | pages= 1339-46 | pmid=17126205 | doi=10.1016/j.ijrobp.2006.07.1388 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17126205 }} </ref><ref name="pmid21855258">{{cite journal| author=Belleflamme M, Penaloza A, Thoma M, Hainaut P, Thys F| title=Mondor disease: a case report in ED. | journal=Am J Emerg Med | year= 2012 | volume= 30 | issue= 7 | pages= 1325.e1-3 | pmid=21855258 | doi=10.1016/j.ajem.2011.06.031 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21855258 }} </ref><ref name="pmid11566698">{{cite journal| author=Shetty MK, Watson AB| title=Mondor's disease of the breast: sonographic and mammographic findings. | journal=AJR Am J Roentgenol | year= 2001 | volume= 177 | issue= 4 | pages= 893-6 | pmid=11566698 | doi=10.2214/ajr.177.4.1770893 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11566698 }} </ref><ref name="pmid23959419">{{cite journal| author=Kadioglu H, Yildiz S, Ersoy YE, Yücel S, Müslümanoğlu M| title=An unusual case caused by a common reason: Mondor's disease by oral contraceptives. | journal=Int J Surg Case Rep | year= 2013 | volume= 4 | issue= 10 | pages= 855-7 | pmid=23959419 | doi=10.1016/j.ijscr.2013.07.026 | pmc=3785854 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23959419 }} </ref> | |||
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Revision as of 18:30, 8 March 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as phyllodes tumor, hamartoma, and adenomyoepithelioma.>[1][2]
Differentiating Fibroadenoma from other Diseases
Fibroadenoma must be differentiated from other diseases that cause breast pain and swelling as shown below:[3][4] [5][6][7][8][9][10][11][12]
| Diseases | Laboratory Findings | Physical Examination | History and Symptoms | Other Findings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Breast milk culture | Biopsy | Breast tenderness | Skin induration | Cordlike vein appearance | History of trauma | Nipple retraction | Nipple discharge | Erythema | Fever | Warmth | Lymphadenopathy | Itching | ||
| Breast abscess | + for bacteria | ✘ | ✔ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | ✔ | ✘ | ✘ | |
| Mastitis | + for bacteria | ✘ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | ✔ | ✔ | ✘ | ||
| Inflammatory breast cancer | ✘ | ✔ | ✔ | ✔ | ✘ | ✔ | ✘ | ✔ | ✘ | ✔ | ✔ | ✔ | *Peau d' orange appearance of the skin
*Metastasis is common. | |
| Galactocele | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✘ | It is differentiated from other masses by US. | |
| Plugged duct | ✘ | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ✘ | ||
| Mondor's syndrome | ✔ | ✔ | ✔ | ✘ | Retracted breast skin and elevation of the skin may be observed. | |||||||||
| Cellulitis | ✘ | ✔ | ✔ | ✔ | ✘ | ✔ | ✔ | ✘ | ||||||
| Fibroadenoma | ✘ | ✔ | ✘ | ✘ | ✘ | ✘ | ✔ | *Peau d' orange skin apperance.
*Enlarged veins on the skin | ||||||
- Fibroadenoma must be differentiated from other diseases that cause a similar clinical presentation, such as:[1][2]
- Phyllodes tumor
- Fibrocystic breast changes
- Hamartoma
- Papillary carcinoma
- Pseudoangiomatous stromal hyperplasia
- Adenomyoepithelioma
References
- ↑ 1.0 1.1 Fibroadenoma. Libre Pathology (2015) http://librepathology.org/wiki/index.php/Fibroadenoma Accessed on January, 29 2016
- ↑ 2.0 2.1 Breast-nonmalignant-Fibroadenoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/breastfibroadenoma.html Accessed on January, 29 2016
- ↑ Greydanus DE, Matytsina L, Gains M (2006). "Breast disorders in children and adolescents". Prim Care. 33 (2): 455–502. doi:10.1016/j.pop.2006.02.002. PMID 16713771.
- ↑ Jahanfar S, Ng CJ, Teng CL (2013). "Antibiotics for mastitis in breastfeeding women". Cochrane Database Syst Rev (2): CD005458. doi:10.1002/14651858.CD005458.pub3. PMID 23450563.
- ↑ Lam E, Chan T, Wiseman SM (2014). "Breast abscess: evidence based management recommendations". Expert Rev Anti Infect Ther. 12 (7): 753–62. doi:10.1586/14787210.2014.913982. PMID 24791941.
- ↑ Kleer CG, van Golen KL, Merajver SD (2000). "Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants". Breast Cancer Res. 2 (6): 423–9. doi:10.1186/bcr89. PMC 138665. PMID 11250736.
- ↑ Dawood S, Merajver SD, Viens P, Vermeulen PB, Swain SM, Buchholz TA; et al. (2011). "International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatment". Ann Oncol. 22 (3): 515–23. doi:10.1093/annonc/mdq345. PMC 3105293. PMID 20603440.
- ↑ Jaiyesimi IA, Buzdar AU, Hortobagyi G (1992). "Inflammatory breast cancer: a review". J Clin Oncol. 10 (6): 1014–24. doi:10.1200/JCO.1992.10.6.1014. PMID 1588366.
- ↑ Indelicato DJ, Grobmyer SR, Newlin H, Morris CG, Haigh LS, Copeland EM; et al. (2006). "Delayed breast cellulitis: an evolving complication of breast conservation". Int J Radiat Oncol Biol Phys. 66 (5): 1339–46. doi:10.1016/j.ijrobp.2006.07.1388. PMID 17126205.
- ↑ Belleflamme M, Penaloza A, Thoma M, Hainaut P, Thys F (2012). "Mondor disease: a case report in ED". Am J Emerg Med. 30 (7): 1325.e1–3. doi:10.1016/j.ajem.2011.06.031. PMID 21855258.
- ↑ Shetty MK, Watson AB (2001). "Mondor's disease of the breast: sonographic and mammographic findings". AJR Am J Roentgenol. 177 (4): 893–6. doi:10.2214/ajr.177.4.1770893. PMID 11566698.
- ↑ Kadioglu H, Yildiz S, Ersoy YE, Yücel S, Müslümanoğlu M (2013). "An unusual case caused by a common reason: Mondor's disease by oral contraceptives". Int J Surg Case Rep. 4 (10): 855–7. doi:10.1016/j.ijscr.2013.07.026. PMC 3785854. PMID 23959419.