Actinomycosis pathophysiology: Difference between revisions
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!Site of Infection | !Site of Infection | ||
!Source of infection | !Source of infection | ||
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!Cervicofacial actinomycosis | !Cervicofacial actinomycosis | ||
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* Dental problems like tooth decay | * Dental problems like tooth decay | ||
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!Thoracic | !Thoracic | ||
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* Transdiaphragmatic or retroperitoneal spread from the abdomen | * Transdiaphragmatic or retroperitoneal spread from the abdomen | ||
* Hematogenous spread | * Hematogenous spread | ||
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!Abdominal actinomycosis | !Abdominal actinomycosis | ||
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* Perforation of the gut (e.g., the colon or appendix) | * Perforation of the gut (e.g., the colon or appendix) | ||
* Surgical manipulation of GI tract | * Surgical manipulation of GI tract | ||
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!Pelvic | !Pelvic | ||
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* Occurs most commonly in woman as the bacteria passes from the female genitals into the pelvis | * Occurs most commonly in woman as the bacteria passes from the female genitals into the pelvis | ||
* Long-term use of IUD type of contraceptive | * Long-term use of IUD type of contraceptive | ||
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!Central nervous system | !Central nervous system | ||
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* Secondary to hematogenous spread from primary infection in the lung, abdomen, or pelvis | * Secondary to hematogenous spread from primary infection in the lung, abdomen, or pelvis | ||
* Direct extension from paranasal sinuses, ears, and cervicofacial regions | * Direct extension from paranasal sinuses, ears, and cervicofacial regions | ||
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Revision as of 18:57, 16 March 2017
Actinomycosis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
- Actinomycosis is caused by the bacteria Actinomyces which is a normal commensal of the human oral cavity but less common in the female genital tract and lower gastrointestinal tract.
- The common clinical forms of are:
- Cervicofacial actinomycosis (lumpy jaw)
- Thoracic actinomycosis
- Abdominal actinomycosis
- Pelvic actinomycosis
- Dermatologic actinomycosis
- Pediatric actinomycosis
- Opthalmological actinomycosis
Pathogenesis
- Actinomyces does not grow in oxygen rich environment. When there is a break through the protective lining surrounding the cavities (from mouth to rectum), the Actinomycetales penetrate through the deeper tissues where the bacteria grow rapidly due to low oxygen levels.[1]
Types | Site of Infection | Source of infection |
---|---|---|
Cervicofacial actinomycosis |
|
|
Thoracic
actinomycosis |
|
|
Abdominal actinomycosis | Abdomen |
|
Pelvic
actinomycosis |
Pelvis |
|
Central nervous system
actinomycosis |
CNS |
|
References
- ↑ Smego RA (1987). "Actinomycosis of the central nervous system". Rev Infect Dis. 9 (5): 855–65. PMID 3317731.