Ischemic colitis causes: Difference between revisions
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{{Ischemic colitis}} | {{Ischemic colitis}} | ||
{{CMG}}; {{AOEIC}} {{CZ}} | {{CMG}}; {{AOEIC}} {{HQ}} {{CZ}} | ||
==Overview== | ==Overview== | ||
Causes of the reduced blood flow can include changes in the systemic circulation (e.g. [[hypotension|low blood pressure]]) or local factors such as [[vasoconstriction|constriction of blood vessels]] or a [[blood clot]]. In most cases, no specific cause can be identified. | Causes of the reduced blood flow can include changes in the systemic circulation (e.g. [[hypotension|low blood pressure]]) or local factors such as [[vasoconstriction|constriction of blood vessels]] or a [[blood clot]]. In most cases, no specific cause can be identified. | ||
==Causes== | ==Causes== | ||
The causes of ischemic colitis are as follows:<ref>Feldman: Sleisenger & Fordtran's Gastrointestinal and Liver Disease, 7th ed., 2002 Saunders, p. 2332.</ref> | |||
Ischemic colitis is often classified according to the underlying cause. Non-occlusive ischemia develops because of [[low blood pressure]] or constriction of the vessels supplying blood to the colon; occlusive ischemia indicates that a [[blood clot]] or other blockage has cut off blood flow to the [[colon]]. In most cases, no specific cause can be identified. | Ischemic colitis is often classified according to the underlying cause. Non-occlusive ischemia develops because of [[low blood pressure]] or constriction of the vessels supplying blood to the colon; occlusive ischemia indicates that a [[blood clot]] or other blockage has cut off blood flow to the [[colon]]. In most cases, no specific cause can be identified. | ||
Revision as of 12:52, 2 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Hamid Qazi, MD, BSc [2] Cafer Zorkun, M.D., Ph.D. [3]
Overview
Causes of the reduced blood flow can include changes in the systemic circulation (e.g. low blood pressure) or local factors such as constriction of blood vessels or a blood clot. In most cases, no specific cause can be identified.
Causes
The causes of ischemic colitis are as follows:[1]
Ischemic colitis is often classified according to the underlying cause. Non-occlusive ischemia develops because of low blood pressure or constriction of the vessels supplying blood to the colon; occlusive ischemia indicates that a blood clot or other blockage has cut off blood flow to the colon. In most cases, no specific cause can be identified.
Non-occlusive Ischemia
- In hemodynamically unstable patients (i.e. shock patients) the mesenteric perfusion may be compromised.
- Low blood pressure
Occlusive Ischemia
- Obstructive atherosclerotic disease
- Superior mesenteric artery occlusion
- Most commonly the embolism is due to atrial fibrillation
- Valvular heart disease including endocarditis
- Myocardial infarction
- Cardiomyopathy
Drugs
- Alosetron
- Cilansetron
- Interferon alfacon-1
- Pegylated interferon alfa-2b
- Ramosetron
- Vasopressors
- Ergotamine
References
- ↑ Feldman: Sleisenger & Fordtran's Gastrointestinal and Liver Disease, 7th ed., 2002 Saunders, p. 2332.