Coxsackie virus: Difference between revisions
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!Clinical Features | !Clinical Features | ||
!Diagnosis | !Diagnosis | ||
!Image | |||
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| rowspan="4" |'''[[Coxscakie A virus]]''' | | rowspan="4" |'''[[Coxscakie A virus]]''' | ||
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*Throat and lesion swabs | *Throat and lesion swabs | ||
*[[Tzanck test]] | *[[Tzanck test]] | ||
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|[[Acute hemorrhagic conjunctivitis]]<ref name="pmid1088513">{{cite journal| author=Yin-Murphy M| title=Simple tests for the diagnosis of picornavirus epidemic conjunctivitis (acute hemorrhagic conjunctivitis). | journal=Bull World Health Organ | year= 1976 | volume= 54 | issue= 6 | pages= 675-9 | pmid=1088513 | doi= | pmc=2366581 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1088513 }} </ref><ref name="pmid26602522">{{cite journal| author=Pinto RD, Lira RP, Arieta CE, Castro RS, Bonon SH| title=The prevalence of adenoviral conjunctivitis at the Clinical Hospital of the State University of Campinas, Brazil. | journal=Clinics (Sao Paulo) | year= 2015 | volume= 70 | issue= 11 | pages= 748-50 | pmid=26602522 | doi=10.6061/clinics/2015(11)06 | pmc=4642493 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26602522 }} </ref><ref name="pmid26077630">{{cite journal| author=Jhanji V, Chan TC, Li EY, Agarwal K, Vajpayee RB| title=Adenoviral keratoconjunctivitis. | journal=Surv Ophthalmol | year= 2015 | volume= 60 | issue= 5 | pages= 435-43 | pmid=26077630 | doi=10.1016/j.survophthal.2015.04.001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26077630 }} </ref> | |[[Acute hemorrhagic conjunctivitis]]<ref name="pmid1088513">{{cite journal| author=Yin-Murphy M| title=Simple tests for the diagnosis of picornavirus epidemic conjunctivitis (acute hemorrhagic conjunctivitis). | journal=Bull World Health Organ | year= 1976 | volume= 54 | issue= 6 | pages= 675-9 | pmid=1088513 | doi= | pmc=2366581 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1088513 }} </ref><ref name="pmid26602522">{{cite journal| author=Pinto RD, Lira RP, Arieta CE, Castro RS, Bonon SH| title=The prevalence of adenoviral conjunctivitis at the Clinical Hospital of the State University of Campinas, Brazil. | journal=Clinics (Sao Paulo) | year= 2015 | volume= 70 | issue= 11 | pages= 748-50 | pmid=26602522 | doi=10.6061/clinics/2015(11)06 | pmc=4642493 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26602522 }} </ref><ref name="pmid26077630">{{cite journal| author=Jhanji V, Chan TC, Li EY, Agarwal K, Vajpayee RB| title=Adenoviral keratoconjunctivitis. | journal=Surv Ophthalmol | year= 2015 | volume= 60 | issue= 5 | pages= 435-43 | pmid=26077630 | doi=10.1016/j.survophthal.2015.04.001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26077630 }} </ref> | ||
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*Positive conjunctival scraping for [[polymerase chain reaction|polymerase chain reaction (PCR)]] | *Positive conjunctival scraping for [[polymerase chain reaction|polymerase chain reaction (PCR)]] | ||
*Positive viral culture of corneal epithelial cells for [[HSV]] | *Positive viral culture of corneal epithelial cells for [[HSV]] | ||
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|[[Herpangina]] | |[[Herpangina]] | ||
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*Pharyngeal viral cultures may be helpful | *Pharyngeal viral cultures may be helpful | ||
* Approximately 1 week after infection, type-specific [[antibodies]] appear in the blood | * Approximately 1 week after infection, type-specific [[antibodies]] appear in the blood | ||
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|[[Aseptic meningitis|Aseptic Meningitis]] | |[[Aseptic meningitis|Aseptic Meningitis]] | ||
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| rowspan="6" |'''[[Coxsackie B virus]]''' | | rowspan="6" |'''[[Coxsackie B virus]]''' | ||
|[[Pericarditis]] | |[[Pericarditis]] | ||
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|[[Myocarditis]] | |[[Myocarditis]] | ||
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|[[Pericardial effusion]] | |[[Pericardial effusion]] | ||
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|[[Pleurodynia]] | |[[Pleurodynia]] | ||
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|[[Hepatitis]] | |[[Hepatitis]] | ||
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|[[Sjogren's syndrome]] | |[[Sjogren's syndrome]] | ||
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Revision as of 18:16, 27 March 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]
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Coxsackie Virus |
Overview
Coxsackie (virus) is a cytolytic virus of the Picornaviridae family, an enterovirus (a group containing the polioviruses, coxsackieviruses, and echoviruses). There are 61 non-polio enteroviruses that can cause disease in humans, of which 23 are Coxsackie A viruses (6 are Coxsackie B viruses). Enterovirus are the second most common viral infectious agents in humans (after the rhinoviruses)
Classification
Coxsackie viruses consist of Coxsackie A virus and Coxsackie B virus. Coxsackie B virus has 6 serotypes, one of the significant serotypes is called Coxsackie B4 virus.
| Coxsackie Virus | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coxsackie A virus | Coxsackie B virus[1] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Common Coxsackie B virus diseases | Coxsackie B4 virus diseases | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| • Hand, foot and mouth disease • Acute hemorrhagic conjunctivitis • Herpangina • Aseptic meningitis | • Pericarditis • Myocarditis • Pericardial effusion • Pleurodynia • Hepatitis • Sjogren's syndorme | • Diabetes mellitus • Acute flaccid myelitis[2] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Differential Diagnosis
Coxsackie A virus and Coxsackie B virus can cause multiple diseases in humans. The wide array of diseases caused by Coxsackie viruses can be differentiated from one another easily on the basis of involvement of the organs systems, clinical presentation and diagnostic techniques.
| Virus Type | Disease | Clinical Features | Diagnosis | Image |
|---|---|---|---|---|
| Coxscakie A virus | Hand foot and mouth disease |
Ulcers in the throat (including tonsils), mouth, and tongue |
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| Acute hemorrhagic conjunctivitis[3][4][5] |
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| Herpangina |
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| Aseptic Meningitis | ||||
| Coxsackie B virus | Pericarditis | |||
| Myocarditis | ||||
| Pericardial effusion | ||||
| Pleurodynia | ||||
| Hepatitis | ||||
| Sjogren's syndrome |
Template:Baltimore classification Template:Viral diseases
- ↑ Fields, Bernard N. (1985). Fields Virology. New York: Raven Press. pp. 739–794. ISBN 0-88167-026-X. Unknown parameter
|coauthors=ignored (help) - ↑ Cho SM, MacDonald S, Frontera JA (2017). "Coxsackie B3/B4-Related Acute Flaccid Myelitis". Neurocrit Care. doi:10.1007/s12028-017-0377-8. PMID 28324262.
- ↑ Yin-Murphy M (1976). "Simple tests for the diagnosis of picornavirus epidemic conjunctivitis (acute hemorrhagic conjunctivitis)". Bull World Health Organ. 54 (6): 675–9. PMC 2366581. PMID 1088513.
- ↑ Pinto RD, Lira RP, Arieta CE, Castro RS, Bonon SH (2015). "The prevalence of adenoviral conjunctivitis at the Clinical Hospital of the State University of Campinas, Brazil". Clinics (Sao Paulo). 70 (11): 748–50. doi:10.6061/clinics/2015(11)06. PMC 4642493. PMID 26602522.
- ↑ Jhanji V, Chan TC, Li EY, Agarwal K, Vajpayee RB (2015). "Adenoviral keratoconjunctivitis". Surv Ophthalmol. 60 (5): 435–43. doi:10.1016/j.survophthal.2015.04.001. PMID 26077630.