Tropical sprue laboratory findings: Difference between revisions
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*Normal transglutaminase levels are present. | *Normal transglutaminase levels are present. | ||
===Approach to a patient with Malabsorption in tropical region=== | ===Approach to a patient with Malabsorption in tropical region=== | ||
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{{familytree | | | | | | | | | | | | | | | A01 | A01= Clinical suspicion of malabsoption syndrome}} | {{familytree | | | | | | | | | | | | | | | A01 | A01= Clinical suspicion of malabsoption syndrome}} | ||
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{{familytree | | | | | | | | | | | | | | | |!| |}} | {{familytree | | | | | | | | | | | | | | | |!| |}} | ||
{{familytree | | | | | | | | | | | | | | | D01 | |D01= Antiendomysial antibodies and villous atrophy suggests celiac disease <br> Breath test for lactase deficiency <br> Microscopy and culture of jejunal aspirate for small bowel bacterial overgrowth <br> Serum immunoglobulin for B-celll deficiency <br> HIV serology}} | {{familytree | | | | | | | | | | | | | | | D01 | |D01= Antiendomysial antibodies and villous atrophy suggests celiac disease <br> Breath test for lactase deficiency <br> Microscopy and culture of jejunal aspirate for small bowel bacterial overgrowth <br> Serum immunoglobulin for B-celll deficiency <br> HIV serology}} | ||
{{familytree | | | | | | | | | | | | | | | |!| |}} | |||
{{familytree | | | | | | | | | | | | | | | E01 | | E01= Once all other possibilities are ruled out, then the diagnosis of tropical sprue is confirmed}} | |||
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==References== | ==References== |
Revision as of 16:41, 11 April 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
All the patients with celiac disease unresponsive to gluten free diet, a diagnosis of tropical sprue must be considered. The lab findings are not specific for tropical sprue as it is a diagnosis of exlclusion.
- Patients with ileal involvement have low vitamin B12 levels
- Normal transglutaminase levels are present.
Approach to a patient with Malabsorption in tropical region
{{familytree | | | | | | | | | | | | | | | C01 | | | | | | | | C01=Confirmatory tests for malabsoption should be done.
Clinical suspicion of malabsoption syndrome | |||||||||||||||||||||||||||||||||||
Initial screening perform: Hemogram Stool Microscopy D-xylose test Fecal fat | |||||||||||||||||||||||||||||||||||
Antiendomysial antibodies and villous atrophy suggests celiac disease Breath test for lactase deficiency Microscopy and culture of jejunal aspirate for small bowel bacterial overgrowth Serum immunoglobulin for B-celll deficiency HIV serology | |||||||||||||||||||||||||||||||||||
Once all other possibilities are ruled out, then the diagnosis of tropical sprue is confirmed | |||||||||||||||||||||||||||||||||||