Esophageal candidiasis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Candida esophagitis is very responsive to antifungal therapy. Complications can be systemic due to spread of infection to the blood stream or local as esophageal stricture and obstruction.

Natural history

Esophageal candidiasis is usually responsive to antifungal treatment with complete resolution. However, recurrence and other cpmplications are frequently encountered due to associated immunosuppression.

Complications

• Systemic spread and fungaemia
• Esophageal perforation
• Tracheo-esophageal fistula
• Esophageal stricture
• Esophageal obstruction

Prognosis

• Prognosis is excellent unless candidaemia and shock occur.