Esophageal candidiasis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Candida esophagitis is very responsive to antifungal therapy. Complications can be systemic due to the spread of infection to the blood stream or local as esophageal stricture and obstruction.

Natural history

If left untreated, complications as esophageal stricture and candidaemia ensue.

Complications

• Systemic spread and fungemia
• Esophageal perforation
• Tracheoesophageal fistula
• Esophageal stricture
• Esophageal obstruction

Prognosis

• Prognosis is excellent unless candidaemia and shock occur.