Esophageal candidiasis medical therapy: Difference between revisions
Jump to navigation
Jump to search
Ahmed Younes (talk | contribs) |
Ahmed Younes (talk | contribs) No edit summary |
||
| Line 9: | Line 9: | ||
===First line antifungal therapy:=== | ===First line antifungal therapy:=== | ||
Oral fluconazole: 200-400 mg * 14-21 | *Oral fluconazole: 200-400 mg * 14-21 | ||
IV fluconazole: 400 mg daily (6mg/kg/day) | *IV fluconazole: 400 mg daily (6mg/kg/day) | ||
AmB-d: 0.3-0.7 mg/day | *AmB-d: 0.3-0.7 mg/day | ||
===In fluconazole refractory patients:=== | ===In fluconazole refractory patients:=== | ||
Itraconazole: 200 mg daily | *Itraconazole: 200 mg daily | ||
Voriconazole: 200 mg twice daily for 14-21 days | *Voriconazole: 200 mg twice daily for 14-21 days | ||
Micafungin: 150 mg daily | *Micafungin: 150 mg daily | ||
Caspofungin: 50 mg daily | *Caspofungin: 50 mg daily | ||
Anidu-lafungin: 200 mg daily | *Anidu-lafungin: 200 mg daily | ||
AmB-d: 0.3 - 0.7 mg/kg daily | *AmB-d: 0.3 - 0.7 mg/kg daily | ||
===Prophylactic (suppressive) therapy:=== | ===Prophylactic (suppressive) therapy:=== | ||
Fluconazole 100-200 3 times/ week | *Fluconazole 100-200 3 times/ week | ||
===HIV patients:=== | ===HIV patients:=== | ||
HAART therapy decreases recurrence of candida esophagitis. | *HAART therapy decreases recurrence of candida esophagitis. | ||
==References== | ==References== | ||
Revision as of 14:22, 31 May 2017
|
Esophageal candidiasis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Esophageal candidiasis medical therapy On the Web |
|
American Roentgen Ray Society Images of Esophageal candidiasis medical therapy |
|
Risk calculators and risk factors for Esophageal candidiasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Medical therapy
- Esophageal candidiasis is almost always treated with systemic antifungals (either parentral or oral)
- A diagnostic trial of antifungal therapy is tried before performing endoscopy in HIV patients (because candida esophagitis is the most common cause of infectious esophagitis). If no improvement within 5-7 days, then endoscopy is indicated.
First line antifungal therapy:
- Oral fluconazole: 200-400 mg * 14-21
- IV fluconazole: 400 mg daily (6mg/kg/day)
- AmB-d: 0.3-0.7 mg/day
In fluconazole refractory patients:
- Itraconazole: 200 mg daily
- Voriconazole: 200 mg twice daily for 14-21 days
- Micafungin: 150 mg daily
- Caspofungin: 50 mg daily
- Anidu-lafungin: 200 mg daily
- AmB-d: 0.3 - 0.7 mg/kg daily
Prophylactic (suppressive) therapy:
- Fluconazole 100-200 3 times/ week
HIV patients:
- HAART therapy decreases recurrence of candida esophagitis.