Cryptococcosis laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
There are no specific laboratory findings associated with | There are no specific laboratory findings associated with [[Cryptococcosis|Cryptococcal]] infection, but it can be diagnosed through culture, [[CSF]] microscopy, or by [[Cryptococcosis|cryptococcal]] antigen (CrAg) detection. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
There are no specific laboratory findings associated with | There are no specific laboratory findings associated with [[Cryptococcosis|Cryptococcal infection]] but it can be diagnosed through culture, [[CSF]] microscopy, or by cryptococcal antigen (CrAg) detection. In patients with [[HIV]]-related cryptococcal [[meningitis]], 55% of [[blood culture]]<nowiki/>s and 95% of [[CSF]] cultures are positive and visible colonies can be detected within 7 days. The opening pressure in the [[CSF]] may be elevated, with pressures ≥25 cm H2O in 60% to 80% of patients. <ref name="aids">Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. Available at http://aidsinfo.nih.gov/contentfiles/lvguidelines/adult_oi.pdf Accessed on December 31, 2015.</ref><ref name="pmid26897067">{{cite journal| author=Maziarz EK, Perfect JR| title=Cryptococcosis. | journal=Infect Dis Clin North Am | year= 2016 | volume= 30 | issue= 1 | pages= 179-206 | pmid=26897067 | doi=10.1016/j.idc.2015.10.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26897067 }} </ref><ref name="pmid26515783">{{cite journal| author=El Fane M, Badaoui L, Ouladlahsen A, Sodqi M, Marih L, Chakib A et al.| title=[Cryptococcosis during HIV infection]. | journal=J Mycol Med | year= 2015 | volume= 25 | issue= 4 | pages= 257-62 | pmid=26515783 | doi=10.1016/j.mycmed.2015.09.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26515783 }} </ref> | ||
==References== | ==References== | ||
Revision as of 16:59, 12 June 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.; Yazan Daaboul, M.D.
Overview
There are no specific laboratory findings associated with Cryptococcal infection, but it can be diagnosed through culture, CSF microscopy, or by cryptococcal antigen (CrAg) detection.
Laboratory Findings
There are no specific laboratory findings associated with Cryptococcal infection but it can be diagnosed through culture, CSF microscopy, or by cryptococcal antigen (CrAg) detection. In patients with HIV-related cryptococcal meningitis, 55% of blood cultures and 95% of CSF cultures are positive and visible colonies can be detected within 7 days. The opening pressure in the CSF may be elevated, with pressures ≥25 cm H2O in 60% to 80% of patients. [1][2][3]
References
- ↑ Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. Available at http://aidsinfo.nih.gov/contentfiles/lvguidelines/adult_oi.pdf Accessed on December 31, 2015.
- ↑ Maziarz EK, Perfect JR (2016). "Cryptococcosis". Infect Dis Clin North Am. 30 (1): 179–206. doi:10.1016/j.idc.2015.10.006. PMID 26897067.
- ↑ El Fane M, Badaoui L, Ouladlahsen A, Sodqi M, Marih L, Chakib A; et al. (2015). "[Cryptococcosis during HIV infection]". J Mycol Med. 25 (4): 257–62. doi:10.1016/j.mycmed.2015.09.008. PMID 26515783.