Adenoiditis classification: Difference between revisions

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===== Adenoiditis classification based on the responsible pathogen and coexisting conditions =====
===== Adenoiditis classification based on the responsible pathogen and coexisting conditions =====
{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
!Pathogen
!Pathogen
!Clinical features
!Clinical features
(other than adenoiditis)
!Treatment
!Treatment
|-
|-
| colspan="2" rowspan="8" |Viral adenoiditis<ref name="pmid21377220">{{cite journal| author=Sadeghi-Shabestari M, Jabbari Moghaddam Y, Ghaharri H| title=Is there any correlation between allergy and adenotonsillar tissue hypertrophy? | journal=Int J Pediatr Otorhinolaryngol | year= 2011 | volume= 75 | issue= 4 | pages= 589-91 | pmid=21377220 | doi=10.1016/j.ijporl.2011.01.026 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21377220  }}</ref><ref name="pmid22870291">{{cite journal| author=Proenca-Modena JL, Pereira Valera FC, Jacob MG, Buzatto GP, Saturno TH, Lopes L et al.| title=High rates of detection of respiratory viruses in tonsillar tissues from children with chronic adenotonsillar disease. | journal=PLoS One | year= 2012 | volume= 7 | issue= 8 | pages= e42136 | pmid=22870291 | doi=10.1371/journal.pone.0042136 | pmc=3411673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22870291  }}</ref><ref name="pmid11249975">{{cite journal |vauthors=Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE, Vassallo J |title=Detection of Epstein-Barr virus in tonsillar tissue of children and the relationship with recurrent tonsillitis |journal=Int. J. Pediatr. Otorhinolaryngol. |volume=58 |issue=1 |pages=9–15 |year=2001 |pmid=11249975 |doi= |url=}}</ref>
| colspan="2" rowspan="7" |Viral adenoiditis<ref name="pmid21377220">{{cite journal| author=Sadeghi-Shabestari M, Jabbari Moghaddam Y, Ghaharri H| title=Is there any correlation between allergy and adenotonsillar tissue hypertrophy? | journal=Int J Pediatr Otorhinolaryngol | year= 2011 | volume= 75 | issue= 4 | pages= 589-91 | pmid=21377220 | doi=10.1016/j.ijporl.2011.01.026 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21377220  }}</ref><ref name="pmid22870291">{{cite journal| author=Proenca-Modena JL, Pereira Valera FC, Jacob MG, Buzatto GP, Saturno TH, Lopes L et al.| title=High rates of detection of respiratory viruses in tonsillar tissues from children with chronic adenotonsillar disease. | journal=PLoS One | year= 2012 | volume= 7 | issue= 8 | pages= e42136 | pmid=22870291 | doi=10.1371/journal.pone.0042136 | pmc=3411673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22870291  }}</ref><ref name="pmid11249975">{{cite journal |vauthors=Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE, Vassallo J |title=Detection of Epstein-Barr virus in tonsillar tissue of children and the relationship with recurrent tonsillitis |journal=Int. J. Pediatr. Otorhinolaryngol. |volume=58 |issue=1 |pages=9–15 |year=2001 |pmid=11249975 |doi= |url=}}</ref>
|''[[Epstein Barr virus|Epstein-barr virus]] (EBV)''
|''[[Epstein Barr virus|Epstein-barr virus]] (EBV)''
|
|
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* Initial Prodrome
* Initial Prodrome
** Common symptoms include: low-grade [[fever]] without chills is seen in nearly all cases, [[Sore throat]], white patches on the tonsils and back of the throat are often seen, [[Muscle weakness]] and sometime extreme [[fatigue]], tender [[lymphadenopathy]], particularly the posterior [[cervical lymph nodes]] are involved
** Common symptoms include: low-grade [[fever]] without chills, [[Sore throat]], white patches on the tonsils and back of the throat, [[Muscle weakness]], [[fatigue]], tender [[lymphadenopathy]], involvement of posterior [[cervical lymph nodes]]
|
|
* Treating symptoms and complications of the infection
* Treating symptoms and complications of the infection
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|[[Enterovirus|''Enterovirus'']]
|[[Enterovirus|''Enterovirus'']]
|
|
* Mild respiratory illness ([[common cold]]), [[Hand, foot and mouth disease]], acute [[hemorrhagic]] [[conjunctivitis]], [[Aseptic meningitis]], [[Myocarditis|myocarditis,]] severe [[neonatal]] [[sepsis]]-like disease, acute [[flaccid paralysis]].<sup>[[Enterovirus|[2]]]</sup>
* Mild respiratory illness ([[common cold]]), [[Hand, foot and mouth disease|hand-and-foot-and-mouth disease]], acute [[hemorrhagic]] [[conjunctivitis]], [[Aseptic meningitis]], [[Myocarditis|myocarditis,]] severe [[neonatal]] [[sepsis]]-like disease, acute [[flaccid paralysis]]<sup>[[Enterovirus|[2]]]</sup>
|
|
* Treating symptoms and complications of the infection
* Treating symptoms and complications of the infection
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|[[Rhinovirus|''Rhinovirus'']]
|[[Rhinovirus|''Rhinovirus'']]
|
|
* [[Pharyngitis|Sore throat]], [[Rhinitis|runny nose]], [[nasal congestion]], [[Sneeze|sneezing]] and [[cough]]; sometimes accompanied by [[Myalgia|muscle aches]], [[Fatigue (medical)|fatigue]], [[malaise]], [[headache]], [[muscle weakness]], or [[Anorexia (symptom)|loss of appetite]].
* [[Pharyngitis|Sore throat]], [[Rhinitis|runny nose]], [[nasal congestion]], [[Sneeze|sneezing]] and [[cough]], sometimes accompanied by [[Myalgia|muscle aches]], [[Fatigue (medical)|fatigue]], [[malaise]], [[headache]], [[muscle weakness]], or [[Anorexia (symptom)|loss of appetite]]
|
|
* [[Interferon]]-alpha
* [[Interferon]]-alpha
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|[[Respiratory syncytial virus|''Respiratory syncytial virus'']]
|[[Respiratory syncytial virus|''Respiratory syncytial virus'']]
|
|
* [[Bronchiolitis]] (inflammation of the small airways in the lung) and [[pneumonia]] in children under 1 year of age
* [[Bronchiolitis]], and [[pneumonia]] in children under 1 year of age
* Recurrent wheezing and [[asthma]]
* Recurrent wheezing and [[asthma]]
|
|
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|[[Cytomegalovirus|''Cytomegalovirus'']]
|[[Cytomegalovirus|''Cytomegalovirus'']]
|
|
* Common symptoms include: Low-grade [[fever]] without chills is seen in nearly all cases, [[Sore throat]]: white patches on the tonsils and back of the throat are often seen, [[Muscle weakness]] and sometime extreme [[fatigue]], tender [[lymphadenopathy]], particularly the posterior [[cervical lymph nodes]] are involved
* Unable to swallow due to [[Tonsils|enlarged tonsils]], [[Cough|dry cough]], [[Loss of appetite]], [[Anorexia]], [[Nausea]] without [[vomiting]], [[Abdominal pain]]-a possible symptom of a potentially fatal rupture of the spleen<sup>[[Mononucleosis history and symptoms|[1]]]</sup> and [[diarrhea]]
 
* Other symptoms that have been described in patients with [[EBV|EBV infection]] include: unable to swallow due to [[Tonsils|enlarged tonsils]], [[Cough|dry cough]], [[Loss of appetite]], [[Anorexia]], [[Nausea]] without [[vomiting]], [[Abdominal pain]]- a possible symptom of a potentially fatal rupture of the spleen<sup>[[Mononucleosis history and symptoms|[1]]]</sup> and [[diarrhea]]
|
|
* Treating symptoms and complications of the infection
* Treating symptoms and complications of the infection
* Ganciclovir
* [[Foscarnet]]
* [[Cidofovir]]
|-
|-
|[[Herpes virus|''Herpes virus'']]
|[[Herpes virus|''Herpes virus'']]
|
|
* Watery [[Blister|blisters]] in the [[skin]] or [[mucous membranes]] (such as the mouth or lips) or on the [[Genital|genitals]].<sup>[[Herpes simplex virus|[1]]]</sup>
* Watery [[Blister|blisters]] in the [[skin]] or [[mucous membranes]] (such as the mouth or lips) or on the [[Genital|genitals]]<sup>[[Herpes simplex virus|[1]]]</sup>
|
|
* Acyclovir
* Acyclovir
* Valacyclovir
* Valacyclovir
* Famcyclovir
* Famcyclovir
|-
|[[Cytomegalovirus|''Cytomegalovirus (CMV)'']]
|
* [[Mononucleosis]] like presentation
* [[Retinitis]]<nowiki/>presents with [[blurred vision]] and [[floaters]]. [[Colitis]] presents with [[abdominal pain]] and [[bloody diarrhea]], [[Pneumonitis]]
|
* Ganciclovir
* [[Foscarnet]]
* [[Cidofovir]]
|-
|-
| rowspan="7" |Bacterial adenoiditis
| rowspan="7" |Bacterial adenoiditis
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|[[Haemophilus influenzae|''Haemophilus influenzae'']]
|[[Haemophilus influenzae|''Haemophilus influenzae'']]
|
|
* [[Bacteremia]], and acute bacterial [[meningitis]]. Occasionally, it causes [[cellulitis]], [[osteomyelitis]], [[epiglottitis]], and joint infections, [[Otitis media]] and [[conjunctivitis]], [[Sinusitis]], [[Pneumonia]]
* [[Bacteremia]], and acute bacterial [[meningitis]], [[epiglottitis]], [[Otitis media]],[[conjunctivitis]], [[Sinusitis]], [[Pneumonia]]
| rowspan="5" |
| rowspan="5" |
* Beta lactamase inhibitor antibiotics
* Beta lactamase inhibitor antibiotics
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|[[Staphylococcus aureus|''Staphylococcus aureus'']]
|[[Staphylococcus aureus|''Staphylococcus aureus'']]
|
|
* [[Atopic dermatitis]]
* [[Toxic shock syndrome]]
* [[Toxic shock syndrome]]
|-
|-
|[[Moraxella catarrhalis|''Moraxella catarrhalis'']]
|[[Moraxella catarrhalis|''Moraxella catarrhalis'']]
|
|
* Otitis media and sinusitis, tracheobronchitis and [[pneumonia]]
* [[Otitis media]], [[sinusitis]], tracheobronchitis, [[pneumonia]]
|-
|-
|[[Streptococcus pneumoniae|''Streptococcus pneumoniae'']]
|[[Streptococcus pneumoniae|''Streptococcus pneumoniae'']]
|
|
* Pneumonia, sinusitis, otitis media, endocarditis
* [[Pneumonia]], [[sinusitis]], [[otitis media]], [[endocarditis]]
|-
|-
|Recurrent<ref name="pmid21377220" /><ref name="Cunningham2000" />
|Recurrent<ref name="pmid21377220" /><ref name="Cunningham2000" />
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|''[[Toxoplasma gondii]]''
|''[[Toxoplasma gondii]]''
|
|
* Symptoms are often [[influenza]]-like: Cervical lymphadenopathy, sore throat, muscle aches and pains that last for a month or more, fever, malaise, night sweats
* Cervical lymphadenopathy, sore throat, muscle aches and pains that last for a month or more, fever, malaise, night sweats
|
|
* [[Pyrimethamine]]
* [[Pyrimethamine]]
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* Allergic [[sinusitis]]
* Allergic [[sinusitis]]
* Redness and [[Itch|itching]] of the [[conjunctiva]] (allergic conjunctivitis)
* Redness and [[Itch|itching]] of the [[conjunctiva]] (allergic conjunctivitis)
* Sneezing, coughing, [[bronchoconstriction]], [[Wheeze|wheezing]] and [[dyspnea]], sometimes outright attacks of [[asthma]], in severe cases the airway constricts due to swelling known as [[angioedema]]
* Sneezing, coughing, [[bronchoconstriction|broncho-constriction]], [[Wheeze|wheezing]] and [[dyspnea]], sometimes outright attacks of [[asthma]], in severe cases the airway constricts due to swelling known as [[angioedema]]
|
|
* [[Antihistamines]]
* [[Antihistamines]]
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|[[GERD]]
|[[GERD]]
|
|
* [[Heartburn]], [[esophagitis]]''',''' [[Stenosis|strictures]], difficulty swallowing ([[dysphagia]]), [[vomiting]], effortless spitting up, [[coughing]], and other respiratory problems
* [[Heartburn]], [[esophagitis]]''',''' [[Stenosis|strictures]], [[dysphagia]], [[vomiting]], effortless spitting up, [[coughing]], and other respiratory problems
|
|
* Lifestyle Modifications
* Lifestyle Modifications
* [[Proton pump inhibitor]]s
* [[Proton pump inhibitor]]s
* [[Antacid]]s
* [[Antacid]]s
* [[Alginic acid]] ([[Gaviscon]])
* [[Alginic acid]]([[Gaviscon]])
|}
|}


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 03:24, 19 June 2017

Adenoiditis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Adenoiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

Adenoiditis may be classified according to duration of symptoms into 3 subtypes: acute adenoiditis, recurrent acute adenoiditis, and chronic/persistant adenoiditis.[1] Adenoiditis may also be classified according to the responsible pathogen/mechanism of disease into 4 subtypes: viral adenoiditis, bacterial adenoiditis, parasitic adenoiditis, and non-infectious adenoiditis.

Classification

Adenoiditis may be classified according to duration of symptoms into 3 subtypes: acute adenoiditis, recurrent acute adenoiditis, and chronic/persistant adenoiditis.[1] Adenoiditis may also be classified according to the responsible pathogen/mechanism of disease into 4 subtypes: viral adenoiditis, bacterial adenoiditis, parasitic adenoiditis, and non-infectious adenoiditis.

Adenoiditis classification based on durtion of symptoms
Subtypes Duration of symptoms
Acute adenoiditis Acute onset of symptoms[2]
Recurrent acute adenoiditis At least 4 or more episodes of acute adenoiditis within a 6 months period[3]
Chronic/persistent adenoiditis Persistent adenoiditis for more than 6 months

Presence of complications

Adenoiditis classification based on the responsible pathogen and coexisting conditions
Pathogen Clinical features

(other than adenoiditis)

Treatment
Viral adenoiditis[4][5][6] Epstein-barr virus (EBV)
  • Asymptomatic
    • In small children, the course of the disease is frequently asymptomatic. Majority of adults infected with mono also remain asymptomatic with serological evidence of past infection.
  • Treating symptoms and complications of the infection
Human adenovirus
  • Treating symptoms and complications of the infection
Enterovirus
  • Treating symptoms and complications of the infection
Rhinovirus
Respiratory syncytial virus
  • Treating symptoms and complications of the infection
  • Ribavirin
Cytomegalovirus
Herpes virus
  • Acyclovir
  • Valacyclovir
  • Famcyclovir
Bacterial adenoiditis Acute [7][8][9][10] Haemophilus influenzae
  • Beta lactamase inhibitor antibiotics
Group A β-hemolytic streptococcus
Staphylococcus aureus
Moraxella catarrhalis
Streptococcus pneumoniae
Recurrent[4][9] Usually due to normal flora pathogens:
Chronic [11][9]
Parasitic adenoiditis Toxoplasma gondii
  • Cervical lymphadenopathy, sore throat, muscle aches and pains that last for a month or more, fever, malaise, night sweats
Non-infectious adenoiditis[4][11][5] Allergies
Asthma
GERD

References

  1. 1.0 1.1 "Head & Neck Surgery--otolaryngology - Google Books".
  2. Havas T, Lowinger D (2002). "Obstructive adenoid tissue: an indication for powered-shaver adenoidectomy". Arch. Otolaryngol. Head Neck Surg. 128 (7): 789–91. PMID 12117336.
  3. Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
  4. 4.0 4.1 4.2 Sadeghi-Shabestari M, Jabbari Moghaddam Y, Ghaharri H (2011). "Is there any correlation between allergy and adenotonsillar tissue hypertrophy?". Int J Pediatr Otorhinolaryngol. 75 (4): 589–91. doi:10.1016/j.ijporl.2011.01.026. PMID 21377220.
  5. 5.0 5.1 Proenca-Modena JL, Pereira Valera FC, Jacob MG, Buzatto GP, Saturno TH, Lopes L; et al. (2012). "High rates of detection of respiratory viruses in tonsillar tissues from children with chronic adenotonsillar disease". PLoS One. 7 (8): e42136. doi:10.1371/journal.pone.0042136. PMC 3411673. PMID 22870291.
  6. Endo LH, Ferreira D, Montenegro MC, Pinto GA, Altemani A, Bortoleto AE, Vassallo J (2001). "Detection of Epstein-Barr virus in tonsillar tissue of children and the relationship with recurrent tonsillitis". Int. J. Pediatr. Otorhinolaryngol. 58 (1): 9–15. PMID 11249975.
  7. Lilja M, Räisänen S, Stenfors LE (1998). "Initial events in the pathogenesis of acute tonsillitis caused by Streptococcus pyogenes". Int. J. Pediatr. Otorhinolaryngol. 45 (1): 15–20. PMID 9804015.
  8. Wessels MR, Bronze MS (1994). "Critical role of the group A streptococcal capsule in pharyngeal colonization and infection in mice". Proc. Natl. Acad. Sci. U.S.A. 91 (25): 12238–42. PMC 45412. PMID 7991612.
  9. 9.0 9.1 9.2 Cunningham, M. W. (2000). "Pathogenesis of Group A Streptococcal Infections". Clinical Microbiology Reviews. 13 (3): 470–511. doi:10.1128/CMR.13.3.470-511.2000. ISSN 0893-8512.
  10. Ellen RP, Gibbons RJ (1972). "M protein-associated adherence of Streptococcus pyogenes to epithelial surfaces: prerequisite for virulence". Infect. Immun. 5 (5): 826–30. PMC 422446. PMID 4564883.
  11. 11.0 11.1 Akcay A, Tamay Z, Dağdeviren E, Guler N, Ones U, Kara CO; et al. (2006). "Childhood asthma and its relationship with tonsillar tissue". Asian Pac J Allergy Immunol. 24 (2–3): 129–34. PMID 17136878.