Hirschsprung's disease natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death | If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. Common complications include [[enterocolitis]], [[intestinal perforation]] and [[short bowel syndrome]]. After appropriate surgical intervention, [[Mortality rate|mortality]] drops significantly. | ||
==Natural history== | ==Natural history== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death | If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. | ||
==Complications== | ==Complications== | ||
* [[Inflammation]] and [[infection]] of the [[intestine]]s ([[enterocolitis]]).<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref> | * [[Inflammation]] and [[infection]] of the [[intestine]]s ([[enterocolitis]]).<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref> | ||
* Intestinal perforation | * Intestinal perforation | ||
* [[Short bowel syndrome]], a condition that can lead to [[malnourishment]] and [[dehydration]] | * [[Short bowel syndrome]], a condition that can lead to [[malnourishment]] and [[dehydration]] | ||
===Possible complications of surgery include=== | ===Possible complications of surgery include=== | ||
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==Prognosis== | ==Prognosis== | ||
*Hirschsprung disease can lead to [[Mortality rate|mortality]] in up to 80% of | *Hirschsprung disease can lead to [[Mortality rate|mortality]] in up to 80% of cases. | ||
*After | *After appropriate surgical intervention, [[Mortality rate|mortality]] drops to 30 %. | ||
==References== | ==References== | ||
Revision as of 22:02, 15 June 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
If left untreated, Hirschsprung disease can lead to enterocolitis and death. Common complications include enterocolitis, intestinal perforation and short bowel syndrome. After appropriate surgical intervention, mortality drops significantly.
Natural history
If left untreated, Hirschsprung disease can lead to enterocolitis and death.
Complications
- Inflammation and infection of the intestines (enterocolitis).[1]
- Intestinal perforation
- Short bowel syndrome, a condition that can lead to malnourishment and dehydration
Possible complications of surgery include
- Wound infection
- Anastomotic leakage
- Intestinal obstruction
- Pelvic abscess
- Chronic obstructive symptoms
- Chronic constipation or diarrhea
Prognosis
- Hirschsprung disease can lead to mortality in up to 80% of cases.
- After appropriate surgical intervention, mortality drops to 30 %.