Strongyloidiasis medical therapy: Difference between revisions
Aditya Ganti (talk | contribs) |
Aditya Ganti (talk | contribs) |
||
| Line 7: | Line 7: | ||
==Treatment== | ==Treatment== | ||
All strongyloidiasis infection (symptomatic and asymptomatic) should be treated with antimicrobial therapy. | All strongyloidiasis infection (symptomatic and asymptomatic) should be treated with antimicrobial therapy. Due to the high rate of reinfection, it is sometimes necessary to repeat antimicrobial therapy | ||
===Antimicrobial Regimen=== | ===Antimicrobial Regimen=== | ||
*Strongyloides stercoralis <ref name="pmid8483992">{{cite journal| author=Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR| title=Albendazole is effective treatment for chronic strongyloidiasis. | journal=Q J Med | year= 1993 | volume= 86 | issue= 3 | pages= 191-5 | pmid=8483992 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8483992 }} </ref> | *Strongyloides stercoralis <ref name="pmid8483992">{{cite journal| author=Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR| title=Albendazole is effective treatment for chronic strongyloidiasis. | journal=Q J Med | year= 1993 | volume= 86 | issue= 3 | pages= 191-5 | pmid=8483992 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8483992 }} </ref> | ||
Revision as of 16:25, 27 June 2017
|
Strongyloidiasis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Strongyloidiasis medical therapy On the Web |
|
American Roentgen Ray Society Images of Strongyloidiasis medical therapy |
|
Risk calculators and risk factors for Strongyloidiasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
The drug of choice for the treatment of uncomplicated strongyloidiasis is ivermectin with albendazole as the alternative. All patients who are at risk of disseminated strongyloidiasis should be treated.[1]
Treatment
All strongyloidiasis infection (symptomatic and asymptomatic) should be treated with antimicrobial therapy. Due to the high rate of reinfection, it is sometimes necessary to repeat antimicrobial therapy
Antimicrobial Regimen
- Strongyloides stercoralis [2]
- Preferred regimen (1): Ivermectin 200 mcg/kg/day PO qd for 2 days or two doses 2 weeks apart from each other[3]
- Alternative regimen (1): Albendazole 400 mg PO bid for 3-7 days
- Alternative regimen (2): Nitazoxanide 500 mg bid for 3 days (adolescents and adults); 200mg bid for 3 days (children 4-11 yrs of age); 100mg PO bid for 3 days (children 1-3 yrs of age)
- Alternative regimen (3): Levamisole 150 mg PO single dose. The pediatric dose is 2.5 mg/kg PO daily
- Alternative regimen (4): Pyrantel pamoate 11 mg/kg single dose PO, maximum 1.0 g
- Alternative regimen (5): Piperazine citrate 75 mg/kg/day for 2 days, maximum 3.5 g/day
Management of Intestinal obstruction
Intestinal obstruction due to strongyloidiasis should be managed conservatively by:
- Nasogastric decompression
- Fluid and electrolyte repletion
- Antihelminthic therapy once bowel motility is restored. Piperazine causes flaccid paralysis of the worms and this can help relieve the obstruction through rapid expulsion of the worms.
- Complete obstruction with inadequate decompression, lack of response within an interval of 24-48 hrs, volvulus, intussusception or perforation should be managed surgically.
References
- ↑ http://www.dpd.cdc.gov/dpdx/HTML/Strongyloidiasis.htm
- ↑ Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR (1993). "Albendazole is effective treatment for chronic strongyloidiasis". Q J Med. 86 (3): 191–5. PMID 8483992.
- ↑ "WGO Practice Guideline Management of Strongyloidiasis" (PDF).