Mastoiditis pathophysiology: Difference between revisions

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==Overview==
==Overview==
The middle ear and mastoid air cells are connected to each other. The bacteria may be transmitted to the mastoid air cells. The inflammation and fluid and bacteria accumulation in mastoid cavities can cause periosteitis and then mastoid bony structure destruction. <ref name="pmid197344392">{{cite journal|year=2010|title=Clinical strategies for the management of acute mastoiditis in the pediatric population|url=|journal=Clin Pediatr (Phila)|volume=49|issue=2|pages=110–5|doi=10.1177/0009922809344349|pmid=19734439|vauthors=Lin HW, Shargorodsky J, Gopen Q}}</ref>
Acute mastoiditis is one of intratemporal complication of [[acute otitis media]] <ref name="pmid15967073">{{cite journal |vauthors=Leskinen K |title=Complications of acute otitis media in children |journal=Curr Allergy Asthma Rep |volume=5 |issue=4 |pages=308–12 |year=2005 |pmid=15967073 |doi= |url=}}</ref>


== Pathogenesis ==
== Pathogenesis ==

Revision as of 15:45, 22 June 2017

Mastoiditis Microchapters

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Overview

Historical Perspective

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Pathophysiology

Causes

Differentiating Mastoiditis from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

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Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Acute mastoiditis is one of intratemporal complication of acute otitis media [1]

Pathogenesis

  • Most common bacteria causing acute Mastoiditis Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus
  • The number of pneumococcal isolates and the percentage of isolates with high-level penicillin resistance from cultures taken from children with OM or mastoiditis for clinical indications have decreased following PCV13 use, largely due to decreases in serotype 19A isolates. [2]
  • Staphylococci, Pseudomonas spp. and polymicrobials present predominantly seen in non-acute Mastoiditis.[3]
  • Pseudomonas aeruginosa may be find in children with acute mastoiditis as a consequence of recurrent acute otitis media and antibiotic use[3]

References

  1. Leskinen K (2005). "Complications of acute otitis media in children". Curr Allergy Asthma Rep. 5 (4): 308–12. PMID 15967073.
  2. Kaplan SL, Center KJ, Barson WJ, Ling-Lin P, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Trammel J, Gruber WC, Hulten KG, Mason EO (2015). "Multicenter surveillance of Streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate vaccine era". Clin. Infect. Dis. 60 (9): 1339–45. doi:10.1093/cid/civ067. PMID 25648240.
  3. 3.0 3.1 Chien JH, Chen YS, Hung IF, Hsieh KS, Wu KS, Cheng MF (2012). "Mastoiditis diagnosed by clinical symptoms and imaging studies in children: disease spectrum and evolving diagnostic challenges". J Microbiol Immunol Infect. 45 (5): 377–81. doi:10.1016/j.jmii.2011.12.008. PMID 22578647.

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