Mastoiditis pathophysiology: Difference between revisions

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==Overview==
==Overview==
Acute mastoiditis is one of intratemporal complication of [[acute otitis media]] <ref name="pmid15967073">{{cite journal |vauthors=Leskinen K |title=Complications of acute otitis media in children |journal=Curr Allergy Asthma Rep |volume=5 |issue=4 |pages=308–12 |year=2005 |pmid=15967073 |doi= |url=}}</ref>
Acute mastoiditis infection of the temporal bone mostly after otitis media of less than one month. The mechanism of spread to mastoid air cells is by direct erosion of bone or through the mastoid emissary veins. Impaired air cell drainage in this context causes mastoiditis.<ref name="pmid19758711">{{cite journal |vauthors=Pang LH, Barakate MS, Havas TE |title=Mastoiditis in a paediatric population: a review of 11 years experience in management |journal=Int. J. Pediatr. Otorhinolaryngol. |volume=73 |issue=11 |pages=1520–4 |year=2009 |pmid=19758711 |doi=10.1016/j.ijporl.2009.07.003 |url=}}</ref>


== Pathogenesis ==
== Pathogenesis ==

Revision as of 15:58, 22 June 2017

Mastoiditis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Mastoiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Acute mastoiditis infection of the temporal bone mostly after otitis media of less than one month. The mechanism of spread to mastoid air cells is by direct erosion of bone or through the mastoid emissary veins. Impaired air cell drainage in this context causes mastoiditis.[1]

Pathogenesis

  • Most common bacteria causing acute Mastoiditis Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus
  • The number of pneumococcal isolates and the percentage of isolates with high-level penicillin resistance from cultures taken from children with OM or mastoiditis for clinical indications have decreased following PCV13 use, largely due to decreases in serotype 19A isolates. [2]
  • Staphylococci, Pseudomonas spp. and polymicrobials present predominantly seen in non-acute Mastoiditis.[3]
  • Pseudomonas aeruginosa may be find in children with acute mastoiditis as a consequence of recurrent acute otitis media and antibiotic use[3]

References

  1. Pang LH, Barakate MS, Havas TE (2009). "Mastoiditis in a paediatric population: a review of 11 years experience in management". Int. J. Pediatr. Otorhinolaryngol. 73 (11): 1520–4. doi:10.1016/j.ijporl.2009.07.003. PMID 19758711.
  2. Kaplan SL, Center KJ, Barson WJ, Ling-Lin P, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Trammel J, Gruber WC, Hulten KG, Mason EO (2015). "Multicenter surveillance of Streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate vaccine era". Clin. Infect. Dis. 60 (9): 1339–45. doi:10.1093/cid/civ067. PMID 25648240.
  3. 3.0 3.1 Chien JH, Chen YS, Hung IF, Hsieh KS, Wu KS, Cheng MF (2012). "Mastoiditis diagnosed by clinical symptoms and imaging studies in children: disease spectrum and evolving diagnostic challenges". J Microbiol Immunol Infect. 45 (5): 377–81. doi:10.1016/j.jmii.2011.12.008. PMID 22578647.

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