Strongyloidiasis natural history, complications and prognosis: Difference between revisions
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{{Strongyloidiasis}} | {{Strongyloidiasis}} | ||
==Overview== | ==Overview== | ||
If left untreated, the subclinical strongyloidiasis can disseminate and transform into hyper infection syndrome with a mortality rate of 90%. Complications that can develop as a result of strongyloidiasis are disseminated strongyloidiasis, especially in patients with HIV or an otherwise weakened immune system, eosinophilic pneumonia and [[malnutrition]] due to problems absorbing nutrients from the gastrointestinal tract ([[malabsorption]]). With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system.<ref name="pmid27213420">{{cite journal |vauthors=Beknazarova M, Whiley H, Ross K |title=Strongyloidiasis: A Disease of Socioeconomic Disadvantage |journal=Int J Environ Res Public Health |volume=13 |issue=5 |pages= |year=2016 |pmid=27213420 |pmc=4881142 |doi=10.3390/ijerph13050517 |url=}}</ref> | If left untreated, the subclinical [[strongyloidiasis]] can disseminate and transform into hyper infection syndrome with a [[mortality]] rate of 90%. Complications that can develop as a result of [[strongyloidiasis]] are disseminated [[strongyloidiasis]], especially in patients with [[HIV]] or an otherwise weakened immune system, [[eosinophilic pneumonia]] and [[malnutrition]] due to problems absorbing nutrients from the [[gastrointestinal tract]] ([[malabsorption]]). With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system.<ref name="pmid27213420">{{cite journal |vauthors=Beknazarova M, Whiley H, Ross K |title=Strongyloidiasis: A Disease of Socioeconomic Disadvantage |journal=Int J Environ Res Public Health |volume=13 |issue=5 |pages= |year=2016 |pmid=27213420 |pmc=4881142 |doi=10.3390/ijerph13050517 |url=}}</ref> | ||
==Natural history== | ==Natural history== | ||
If left untreated, the subclinical strongyloidiasis can disseminate and transform into hyper infection syndrome with a mortality rate of 90%. | If left untreated, the subclinical [[strongyloidiasis]] can disseminate and transform into hyper infection syndrome with a [[mortality]] rate of 90%. | ||
==Complications== | ==Complications== | ||
Complications that can develop as a result of strongyloidiasis are | Complications that can develop as a result of [[strongyloidiasis]] are | ||
* Disseminated strongyloidiasis, especially in patients with HIV or an otherwise weakened immune system | * [[Strongyloidiasis|Disseminated strongyloidiasis]], especially in patients with [[HIV]] or an otherwise weakened immune system | ||
* Eosinophilic pneumonia | * [[Eosinophilic pneumonia]] | ||
* [[Malnutrition]] due to problems absorbing nutrients from the gastrointestinal tract ([[malabsorption]]) | * [[Malnutrition]] due to problems absorbing nutrients from the [[gastrointestinal tract]] ([[malabsorption]]) | ||
==Prognosis== | ==Prognosis== | ||
With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system. Strongyloidiasis can be severe and life-threatening in persons who: | With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system. [[Strongyloidiasis]] can be severe and life-threatening in persons who: | ||
*People who use oral or intravenous steroids -- such as those with asthma or chronic obstructive pulmonary disease (COPD) exacerbations, lupus, gout, or in persons using steroids for immunosuppression or symptomatic relief | *People who use oral or intravenous [[steroids]] -- such as those with [[asthma]] or [[chronic obstructive pulmonary disease]] ([[COPD]]) exacerbations, [[lupus]], [[gout]], or in persons using [[steroids]] for [[immunosuppression]] or symptomatic relief | ||
*HTLV-1 infection | *[[HTLV-1]] infection | ||
*Have hematologic malignancies such as leukemia or lymphoma | *Have [[hematologic]] [[malignancies]] such as [[leukemia]] or [[lymphoma]] | ||
*Transplant recipients. | *[[Transplant|Transplant recipients.]] | ||
==References== | ==References== | ||
Revision as of 16:11, 30 June 2017
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Overview
If left untreated, the subclinical strongyloidiasis can disseminate and transform into hyper infection syndrome with a mortality rate of 90%. Complications that can develop as a result of strongyloidiasis are disseminated strongyloidiasis, especially in patients with HIV or an otherwise weakened immune system, eosinophilic pneumonia and malnutrition due to problems absorbing nutrients from the gastrointestinal tract (malabsorption). With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system.[1]
Natural history
If left untreated, the subclinical strongyloidiasis can disseminate and transform into hyper infection syndrome with a mortality rate of 90%.
Complications
Complications that can develop as a result of strongyloidiasis are
- Disseminated strongyloidiasis, especially in patients with HIV or an otherwise weakened immune system
- Eosinophilic pneumonia
- Malnutrition due to problems absorbing nutrients from the gastrointestinal tract (malabsorption)
Prognosis
With good treatment, people should make a full recovery. Often Sometimes treatment needs to be repeated. Infections that are severe or widespread often have a poor outcome, especially in people with a weakened immune system. Strongyloidiasis can be severe and life-threatening in persons who:
- People who use oral or intravenous steroids -- such as those with asthma or chronic obstructive pulmonary disease (COPD) exacerbations, lupus, gout, or in persons using steroids for immunosuppression or symptomatic relief
- HTLV-1 infection
- Have hematologic malignancies such as leukemia or lymphoma
- Transplant recipients.
References
- ↑ Beknazarova M, Whiley H, Ross K (2016). "Strongyloidiasis: A Disease of Socioeconomic Disadvantage". Int J Environ Res Public Health. 13 (5). doi:10.3390/ijerph13050517. PMC 4881142. PMID 27213420.