Mastoiditis pathophysiology: Difference between revisions

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{{Mastoiditis}}
{{Mastoiditis}}


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==Overview==
==Overview==
== Pathogenesis ==
 
== Pathophysiology ==
 
=== Pathogenesis ===
Mastoiditis is the infection in the cavities of mastoid process of temporal bone that occurs after otitis media. At birth, the mastoid consists of a single cavity, which is connected to the middle ear by a canal. As the child grows, the mastoid bone becomes pneumatized, resulting in a series of connected cavities, lined by a mucosa diverted from respiratory epithelium. There is a relationship between the middle ear, eustachian tube, and the mastoid. This connection has a fundamental role in the pathogenesis of mastoiditis. In the setting of [[acute otitis media]] the mucosa that lines the middle ear and also mastoid air cells becomes inflamed. In majority cases of [[acute otitis media]] inflammation resolves, but some persist leading to bacterial and fluid accumulation within the mastoid air cells. Gradually, as a result of pressure rising in mastoid, air cell septae may be destroyed and mastoiditis could be proceed to periostitis, cavity abscess and  ostemyelitis.<ref name="pmid197344392">{{cite journal|year=2010|title=Clinical strategies for the management of acute mastoiditis in the pediatric population|url=|journal=Clin Pediatr (Phila)|volume=49|issue=2|pages=110–5|doi=10.1177/0009922809344349|pmid=19734439|vauthors=Lin HW, Shargorodsky J, Gopen Q}}</ref><ref name="pmid197587112">{{cite journal|year=2009|title=Mastoiditis in a paediatric population: a review of 11 years experience in management|url=|journal=Int. J. Pediatr. Otorhinolaryngol.|volume=73|issue=11|pages=1520–4|doi=10.1016/j.ijporl.2009.07.003|pmid=19758711|vauthors=Pang LH, Barakate MS, Havas TE}}</ref>
Mastoiditis is the infection in the cavities of mastoid process of temporal bone that occurs after otitis media. At birth, the mastoid consists of a single cavity, which is connected to the middle ear by a canal. As the child grows, the mastoid bone becomes pneumatized, resulting in a series of connected cavities, lined by a mucosa diverted from respiratory epithelium. There is a relationship between the middle ear, eustachian tube, and the mastoid. This connection has a fundamental role in the pathogenesis of mastoiditis. In the setting of [[acute otitis media]] the mucosa that lines the middle ear and also mastoid air cells becomes inflamed. In majority cases of [[acute otitis media]] inflammation resolves, but some persist leading to bacterial and fluid accumulation within the mastoid air cells. Gradually, as a result of pressure rising in mastoid, air cell septae may be destroyed and mastoiditis could be proceed to periostitis, cavity abscess and  ostemyelitis.<ref name="pmid197344392">{{cite journal|year=2010|title=Clinical strategies for the management of acute mastoiditis in the pediatric population|url=|journal=Clin Pediatr (Phila)|volume=49|issue=2|pages=110–5|doi=10.1177/0009922809344349|pmid=19734439|vauthors=Lin HW, Shargorodsky J, Gopen Q}}</ref><ref name="pmid197587112">{{cite journal|year=2009|title=Mastoiditis in a paediatric population: a review of 11 years experience in management|url=|journal=Int. J. Pediatr. Otorhinolaryngol.|volume=73|issue=11|pages=1520–4|doi=10.1016/j.ijporl.2009.07.003|pmid=19758711|vauthors=Pang LH, Barakate MS, Havas TE}}</ref>



Revision as of 12:49, 30 June 2017

Mastoiditis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Mastoiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Overview

Pathophysiology

Pathogenesis

Mastoiditis is the infection in the cavities of mastoid process of temporal bone that occurs after otitis media. At birth, the mastoid consists of a single cavity, which is connected to the middle ear by a canal. As the child grows, the mastoid bone becomes pneumatized, resulting in a series of connected cavities, lined by a mucosa diverted from respiratory epithelium. There is a relationship between the middle ear, eustachian tube, and the mastoid. This connection has a fundamental role in the pathogenesis of mastoiditis. In the setting of acute otitis media the mucosa that lines the middle ear and also mastoid air cells becomes inflamed. In majority cases of acute otitis media inflammation resolves, but some persist leading to bacterial and fluid accumulation within the mastoid air cells. Gradually, as a result of pressure rising in mastoid, air cell septae may be destroyed and mastoiditis could be proceed to periostitis, cavity abscess and ostemyelitis.[1][2]

Mastoid is near important structures like the facial nerve, sternocleidomastoid muscle, jugular vein, internal carotid artery, sigmoid sinus, brain, and meninges; as a result of this proximity, spreading infection to these places may cause complications

References

  1. Lin HW, Shargorodsky J, Gopen Q (2010). "Clinical strategies for the management of acute mastoiditis in the pediatric population". Clin Pediatr (Phila). 49 (2): 110–5. doi:10.1177/0009922809344349. PMID 19734439.
  2. Pang LH, Barakate MS, Havas TE (2009). "Mastoiditis in a paediatric population: a review of 11 years experience in management". Int. J. Pediatr. Otorhinolaryngol. 73 (11): 1520–4. doi:10.1016/j.ijporl.2009.07.003. PMID 19758711.

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