Chickenpox medical therapy: Difference between revisions
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====Anti-viral Therapy==== | ====Anti-viral Therapy==== | ||
* Anti-viral therapy for chickenpox | * Anti-viral therapy for chickenpox is beneficial if given within the first 24hrs of the appearance of the rash.<ref name="urlA Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJM199111283252203#t=article |title=A Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid1323943">{{cite journal |vauthors=Wallace MR, Bowler WA, Murray NB, Brodine SK, Oldfield EC |title=Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial |journal=Ann. Intern. Med. |volume=117 |issue=5 |pages=358–63 |year=1992 |pmid=1323943 |doi= |url=}}</ref> | ||
* Acyclovir and valacyclovir can be considered for individuals who are two years and above. Acyclovir is preferred over valcyclovir because of its better safety profile. | * Acyclovir and valacyclovir can be considered for individuals who are two years and above. Acyclovir is preferred over valcyclovir because of its better safety profile. | ||
* Acyclovir is given as 20 mg per kg per dose every 6th hourly for age groups of 2 to 12 years and for adolescents. Dose not to exceed 800 mg per day. <ref name="pmid26379165">{{cite journal |vauthors=Kechagia IA, Kalantzi L, Dokoumetzidis A |title=Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling |journal=Pediatr. Infect. Dis. J. |volume=34 |issue=12 |pages=1342–8 |year=2015 |pmid=26379165 |doi=10.1097/INF.0000000000000910 |url=}}</ref> | * Acyclovir is given as 20 mg per kg per dose every 6th hourly for age groups of 2 to 12 years and for adolescents. Dose not to exceed 800 mg per day. <ref name="pmid26379165">{{cite journal |vauthors=Kechagia IA, Kalantzi L, Dokoumetzidis A |title=Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling |journal=Pediatr. Infect. Dis. J. |volume=34 |issue=12 |pages=1342–8 |year=2015 |pmid=26379165 |doi=10.1097/INF.0000000000000910 |url=}}</ref> | ||
Revision as of 00:36, 30 June 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
There is no definitive treatment for chicken pox, supportive treatment to minimize discomfort and pruritus.
Medical Therapy
Symptomatic treatment
- Mild sodium bicarbonate baths, antihistamine medication to help ease itching
- Acetaminophen to reduce fever.
- Ibuprofen
- ASPIRIN MUST NOT BE GIVEN to children with chickenpox to avoid potentially fatal Reye's Syndrome. [1][2]
- Topical application of calamine lotion [3] Calamine lotion is no longer recommended due to its excessive drying nature.
- Maintaining adequate hydration
- Intravenous Immunoglobulin therapy is also considered in pregnant women, immunocompromised patients and newborns who are not vaccinated.
Anti-viral Therapy
- Anti-viral therapy for chickenpox is beneficial if given within the first 24hrs of the appearance of the rash.[4][5]
- Acyclovir and valacyclovir can be considered for individuals who are two years and above. Acyclovir is preferred over valcyclovir because of its better safety profile.
- Acyclovir is given as 20 mg per kg per dose every 6th hourly for age groups of 2 to 12 years and for adolescents. Dose not to exceed 800 mg per day. [6]
Medications to avoid
References
- ↑ US Centers for Disease Control and Prevention. "Varicella Treatment Questions & Answers". CDC Guidelines. CDC. Retrieved 2007-8-23. Check date values in:
|accessdate=(help) - ↑ Somekh E, Dalal I, Shohat T, Ginsberg GM, Romano O (2002). "The burden of uncomplicated cases of chickenpox in Israel". J. Infect. 45 (1): 54–7. PMID 12217733.
- ↑ Tebruegge M, Kuruvilla M, Margarson I (2006). "Does the use of calamine or antihistamine provide symptomatic relief from pruritus in children with varicella zoster infection?". Arch. Dis. Child. 91 (12): 1035–6. doi:10.1136/adc.2006.105114. PMID 17119083. Text "format-Abstract" ignored (help)
- ↑ "A Controlled Trial of Acyclovir for Chickenpox in Normal Children — NEJM".
- ↑ Wallace MR, Bowler WA, Murray NB, Brodine SK, Oldfield EC (1992). "Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial". Ann. Intern. Med. 117 (5): 358–63. PMID 1323943.
- ↑ Kechagia IA, Kalantzi L, Dokoumetzidis A (2015). "Extrapolation of Valacyclovir Posology to Children Based on Pharmacokinetic Modeling". Pediatr. Infect. Dis. J. 34 (12): 1342–8. doi:10.1097/INF.0000000000000910. PMID 26379165.