Echinococcosis history and symptoms: Difference between revisions

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{{CMG}} '''Associate Editor-In-Chief:''' {{CZ}}; {{KD}}
{{CMG}} '''Associate Editor-In-Chief:''' {{CZ}}; {{KD}}
==Overview==
==Overview==
Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.<ref name="pmid3362862">{{cite journal |vauthors=Chakraborty R, Smouse PE |title=Recombination of haplotypes leads to biased estimates of admixture proportions in human populations |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue=9 |pages=3071–4 |year=1988 |pmid=3362862 |pmc=280145 |doi= |url=}}</ref>
Persons with [[echinococcosis]] often remain asymptomatic. The clinical presentation of [[echinococcosis]] [[infection]] depends upon the site of the [[cysts]] and their size. The [[cysts]] are mainly found in the [[liver]] and [[lungs]] but can also appear in the [[brain]], [[eyes]], [[spleen]], [[Kidney|kidneys]], [[heart]], [[bone]], and [[central nervous system]]. [[Cyst]] rupture is most frequently caused by [[Physical trauma|trauma]] and may cause mild to severe [[Anaphylactic reaction|anaphylactic reactions]], even death, as a result of the release of [[cystic]] [[fluid]].<ref name="pmid3362862">{{cite journal |vauthors=Chakraborty R, Smouse PE |title=Recombination of haplotypes leads to biased estimates of admixture proportions in human populations |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue=9 |pages=3071–4 |year=1988 |pmid=3362862 |pmc=280145 |doi= |url=}}</ref>


==History and Symptoms==
==History and Symptoms==
Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.
Persons with [[echinococcosis]] often remain [[asymptomatic]]. The clinical presentation of [[echinococcosis]] [[infection]] depends upon the site of the [[Cyst|cysts]] and their size. The [[cysts]] are mainly found in the [[liver]] and [[lungs]] but can also appear in the [[brain]], [[eyes]], [[spleen]], [[Kidney|kidneys]], [[heart]], [[bone]], and [[central nervous system]]. [[Cyst]] rupture is most frequently caused by [[trauma]] and may cause mild to severe [[Anaphylactic reaction|anaphylactic reactions]], even death, as a result of the release of [[cystic]] [[fluid]].


{| class="wikitable"
{| class="wikitable"
Line 13: Line 13:
!Symtpoms
!Symtpoms
|-
|-
|Liver involvement 
|[[Liver]] involvement 
|
|
* No symptoms (if cysts are less than <10cms)
* No symptoms (if cysts are less than <10cms)
* Hepatomegaly  
* [[Hepatomegaly]]
* Right upper quadrant pain
* [[Right upper quadrant pain]]
* Nausea, and vomiting  
* [[Nausea and vomiting]]
* Cysts can rupture into the biliary tree and produce biliary colic, obstructive jaundice, cholangitis, or pancreatitis
* [[Cysts]] can rupture into the [[biliary tree]] and produce [[biliary colic]], [[obstructive jaundice]], [[cholangitis]], or [[pancreatitis]]
* Mass effects on the bile ducts, portal and hepatic veins, or on the inferior vena cava can result in cholestasis, portal hypertension, venous obstruction, or the Budd-Chiari syndrome.
* Mass effects on the [[bile ducts]], [[portal]] and [[hepatic veins]], or on the [[inferior vena cava]] can result in [[cholestasis]], [[portal hypertension]], [[venous]] [[obstruction]], or the [[Budd-Chiari syndrome]].
|-
|-
| rowspan="2" |Lung involvement 
| rowspan="2" |[[Lung]] involvement 
|Most common
|Most common
* Cough  
* [[Cough]]  
* Chest pain  
* [[Chest pain]]  
* Dyspnea 
* [[Dyspnea]] 
* Hemoptysis . 
* [[Hemoptysis]]
|-
|-
|Less common
|Less common
* Malaise
* [[Malaise]]
* Nausea and vomiting
* [[Nausea and vomiting]]
* Thoracic deformations
* [[Thoracic]] deformations
|-
|-
|Heart 
|[[Heart]] 
|
|
* Mechanical rupture of valves
* Mechanical rupture of valves
* Pericardial tamponade 
* [[Pericardial tamponade]]
|-
|-
|CNS
|[[CNS]]
|
|
* Seizures  
* [[Seizure|Seizures]]
* Raised intracranial pressure
* [[Raised intracranial pressure]]
* Infection of the spinal cord  results in spinal cord compression
* [[Infection]] of the [[spinal cord]] results in [[spinal cord compression]]
|-
|-
|Renal
|Renal
|
|
* Hematuria and flank pain
* [[Hematuria]] and [[flank pain]]


* Nephrotic syndrome due to to immune complex deposition
* [[Nephrotic syndrome]] due to [[immune complex]] deposition
|-
|-
|
|

Revision as of 19:59, 24 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Kalsang Dolma, M.B.B.S.[3]

Overview

Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.[1]

History and Symptoms

Persons with echinococcosis often remain asymptomatic. The clinical presentation of echinococcosis infection depends upon the site of the cysts and their size. The cysts are mainly found in the liver and lungs but can also appear in the brain, eyes, spleen, kidneys, heart, bone, and central nervous system. Cyst rupture is most frequently caused by trauma and may cause mild to severe anaphylactic reactions, even death, as a result of the release of cystic fluid.

System Symtpoms
Liver involvement 
Lung involvement  Most common
Less common
Heart 
CNS
Renal

References

  1. Chakraborty R, Smouse PE (1988). "Recombination of haplotypes leads to biased estimates of admixture proportions in human populations". Proc. Natl. Acad. Sci. U.S.A. 85 (9): 3071–4. PMC 280145. PMID 3362862.

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