Diabetes insipidus historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
*In 1670s Thomas Willis, noted the difference in taste of urine from polyuric subjects compared with healthy individuals and started the differentiation of Diabetes Mellitus from Diabetes Insipidus. | |||
*In 1794, Johann Peter Frank described polyuric patients excreting nonsaccharine urine and introduced the term of Diabetes Insipidus. | |||
*In 1913, a historical milestone was achieved when Farini successfully used posterior pituitary extracts to treat Diabetes Insipidus. | |||
*In the early 1920s the available evidence indicated Diabetes Insipidus as a disorder of the pituitary gland. | |||
=== | *In the early 1928, De Lange first observed that some patients with Diabetes Insipidus did not respond to posterior pituitary extracts. | ||
*Forssman and Waring in 1945 established that the kidney had a critical role for these forms of Diabetes Insipidus resistant to this treatment. | |||
*In 1947 Williams and Henry introduced the term Nephrogenic Diabetes Insipidus for the congenital syndrome characterized by polyuria and renal concentrating defect resistant to vasopressin. | |||
*In 1955, du Vigneaud received the 1955 Nobel Prize in chemistry for the first synthesis of the hormone vasopressin representing a milestone for the treatment of Central Diabetes Insipidus.<ref name="pmid26913870">{{cite journal |vauthors=Valenti G, Tamma G |title=History of Diabetes Insipidus |journal=G Ital Nefrol |volume=33 Suppl 66 |issue= |pages=33.S66.1 |year=2016 |pmid=26913870 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
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Overview
Historical Perspective
- In 1670s Thomas Willis, noted the difference in taste of urine from polyuric subjects compared with healthy individuals and started the differentiation of Diabetes Mellitus from Diabetes Insipidus.
- In 1794, Johann Peter Frank described polyuric patients excreting nonsaccharine urine and introduced the term of Diabetes Insipidus.
- In 1913, a historical milestone was achieved when Farini successfully used posterior pituitary extracts to treat Diabetes Insipidus.
- In the early 1920s the available evidence indicated Diabetes Insipidus as a disorder of the pituitary gland.
- In the early 1928, De Lange first observed that some patients with Diabetes Insipidus did not respond to posterior pituitary extracts.
- Forssman and Waring in 1945 established that the kidney had a critical role for these forms of Diabetes Insipidus resistant to this treatment.
- In 1947 Williams and Henry introduced the term Nephrogenic Diabetes Insipidus for the congenital syndrome characterized by polyuria and renal concentrating defect resistant to vasopressin.
- In 1955, du Vigneaud received the 1955 Nobel Prize in chemistry for the first synthesis of the hormone vasopressin representing a milestone for the treatment of Central Diabetes Insipidus.[1]