Heparin-induced thrombocytopenia CT: Difference between revisions
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CT scan is not specific for a diagnosis of HIT, but a CT scan can be useful to assess for thrombotic manifestations of HIT, such as stroke, pulmonary embolism, mesenteric ischemia, intraabdominal or retroperitoneal bleeding, or acute limb ischemia. | CT scan is not specific for a diagnosis of HIT, but a CT scan can be useful to assess for thrombotic manifestations of HIT, such as stroke, pulmonary embolism, mesenteric ischemia, intraabdominal or retroperitoneal bleeding, or acute limb ischemia. | ||
* '''CT of the head''' in a patient with thrombotic stroke can show hypodensity suggestive of infarcted brain tissue. Alternatively, intracranial bleeding from thrombocytopenia will present radiographically as a hyperdensity on CT. | * '''CT of the head''' in a patient with thrombotic stroke can show hypodensity suggestive of infarcted brain tissue. Alternatively, intracranial bleeding from thrombocytopenia will present radiographically as a hyperdensity on CT.<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | ||
* '''CT of the chest''' in a patient with pulmonary embolism from HIT can show Hampton's hump, Westermark's sign, or Fleischner's sign, similar to a chest X-ray. | * '''CT of the chest''' in a patient with pulmonary embolism from HIT can show Hampton's hump, Westermark's sign, or Fleischner's sign, similar to a chest X-ray.<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | ||
* '''CT of the abdomen or pelvis''' in a patient with mesenteric ischemia can show evidence of bowel necrosis. A retroperitoneal bleed or intraabdominal bleed from thrombocytopenia will show hyperdensity in the area of the bleeding. | * '''CT of the abdomen or pelvis''' in a patient with mesenteric ischemia can show evidence of bowel necrosis. A retroperitoneal bleed or intraabdominal bleed from thrombocytopenia will show hyperdensity in the area of the bleeding. | ||
Revision as of 23:53, 14 July 2017
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Heparin-induced thrombocytopenia CT On the Web |
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American Roentgen Ray Society Images of Heparin-induced thrombocytopenia CT |
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Directions to Hospitals Treating Heparin-induced thrombocytopenia |
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Risk calculators and risk factors for Heparin-induced thrombocytopenia CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]
Overview
CT
CT scan is not specific for a diagnosis of HIT, but a CT scan can be useful to assess for thrombotic manifestations of HIT, such as stroke, pulmonary embolism, mesenteric ischemia, intraabdominal or retroperitoneal bleeding, or acute limb ischemia.
- CT of the head in a patient with thrombotic stroke can show hypodensity suggestive of infarcted brain tissue. Alternatively, intracranial bleeding from thrombocytopenia will present radiographically as a hyperdensity on CT.[1]
- CT of the chest in a patient with pulmonary embolism from HIT can show Hampton's hump, Westermark's sign, or Fleischner's sign, similar to a chest X-ray.[1]
- CT of the abdomen or pelvis in a patient with mesenteric ischemia can show evidence of bowel necrosis. A retroperitoneal bleed or intraabdominal bleed from thrombocytopenia will show hyperdensity in the area of the bleeding.
- CT of the extremities in a patient with acute limb ischemic can show evidence of an ischemic limb. CT should be done with a runoff study to visualize the passage of dye through the arterial or venous circulation of the extremity.
Reference
- ↑ 1.0 1.1 Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S; et al. (2012). "Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e495S–e530S. doi:10.1378/chest.11-2303. PMC 3278058. PMID 22315270.