Hashimoto's thyroiditis classification: Difference between revisions
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==Classification== | ==Classification== | ||
#Primary | |||
#*Primary HT is the most common form of thyroiditis and comprises the cases that do not currently have identifiable causes. Primary HT encompasses a spectrum of six main types: | |||
#**Classic form | |||
#**Fibrous variant | |||
#**IgG4-related variant | |||
#**Juvenile form | |||
#**Hashitoxicosis | |||
#**Painless (or silent) thyroiditis | |||
#Secondary | |||
#*Secondary HT is of more recent description. It includes the forms | |||
where an etiologic agent can be clearly identified. It is more commonly | |||
#**Iatrogenic and induced by the administration of | |||
#**Immunomodulatory drugs (e.g, interferon-alpha.) | |||
#**Monoclonal antibodies that block CTLA-4 | |||
#**Cancer vaccines | |||
In rare cases, Hashimoto's thyroiditis may be associated with other endocrine disorders caused by the immune system. On the basis of the involvement of other endocrine disease involvements, Hashimoto's thyroiditis may be classified under the polyglandular autoimmune syndromes. <ref name="pmid19411300">{{cite journal |vauthors=Kahaly GJ |title=Polyglandular autoimmune syndromes |journal=Eur. J. Endocrinol. |volume=161 |issue=1 |pages=11–20 |year=2009 |pmid=19411300 |doi=10.1530/EJE-09-0044 |url=}}</ref> | In rare cases, Hashimoto's thyroiditis may be associated with other endocrine disorders caused by the immune system. On the basis of the involvement of other endocrine disease involvements, Hashimoto's thyroiditis may be classified under the polyglandular autoimmune syndromes. <ref name="pmid19411300">{{cite journal |vauthors=Kahaly GJ |title=Polyglandular autoimmune syndromes |journal=Eur. J. Endocrinol. |volume=161 |issue=1 |pages=11–20 |year=2009 |pmid=19411300 |doi=10.1530/EJE-09-0044 |url=}}</ref> | ||
#Type 2 polyglandular autoimmune syndrome (PGA II). | #Type 2 polyglandular autoimmune syndrome (PGA II). | ||
Revision as of 21:00, 18 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
On the basis of involvement with other endocrine diseases, Hashimoto's thyroiditis can be categorized under the polyglandular disorders.
Classification
- Primary
- Primary HT is the most common form of thyroiditis and comprises the cases that do not currently have identifiable causes. Primary HT encompasses a spectrum of six main types:
- Classic form
- Fibrous variant
- IgG4-related variant
- Juvenile form
- Hashitoxicosis
- Painless (or silent) thyroiditis
- Primary HT is the most common form of thyroiditis and comprises the cases that do not currently have identifiable causes. Primary HT encompasses a spectrum of six main types:
- Secondary
- Secondary HT is of more recent description. It includes the forms
where an etiologic agent can be clearly identified. It is more commonly
- Iatrogenic and induced by the administration of
- Immunomodulatory drugs (e.g, interferon-alpha.)
- Monoclonal antibodies that block CTLA-4
- Cancer vaccines
In rare cases, Hashimoto's thyroiditis may be associated with other endocrine disorders caused by the immune system. On the basis of the involvement of other endocrine disease involvements, Hashimoto's thyroiditis may be classified under the polyglandular autoimmune syndromes. [1]
- Type 2 polyglandular autoimmune syndrome (PGA II).
- Hashimoto's disease/hypothyroidism
- Adrenal insufficiency
- Type 1 diabetes
- Type 1 polyglandular autoimmune syndrome (PGA I):
- Hashimoto's disease/hypothyroidism
- Adrenal insufficiency
- Fungal infections of the mouth and nails
- Hypoparathyroidism
References
- ↑ Kahaly GJ (2009). "Polyglandular autoimmune syndromes". Eur. J. Endocrinol. 161 (1): 11–20. doi:10.1530/EJE-09-0044. PMID 19411300.