Hashimoto's thyroiditis causes: Difference between revisions
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===Less common cause=== | ===Less common cause=== | ||
*Immunomodulatory drugs (e.g, interferon-alpha.) | |||
*Monoclonal antibodies that block CTLA-4 | |||
*Cancer vaccines | |||
*Micro RNA involvement. | *Micro RNA involvement. | ||
*Polyglandular diseases. | *Polyglandular diseases. | ||
Revision as of 21:10, 18 July 2017
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Hashimoto's thyroiditis Microchapters |
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Hashimoto's thyroiditis causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Hashimoto's thyroiditis may be caused by either T cells and B cells auto activation, genetic factors, and autoimmune antibodies against thyrotropin receptors.
Causes
The causes involved in the development of Hashimoto's thyroiditis are:[1]
Common causes
- Autoantibodies against Thyroid peroxidase and thyroglobulin.
- Abnormalities in the suppressor T cells and regulatory T cells.
- HLA-B* 46:01, HLA-A* 02:07 and HLA-DRB4 involvement.
Less common cause
- Immunomodulatory drugs (e.g, interferon-alpha.)
- Monoclonal antibodies that block CTLA-4
- Cancer vaccines
- Micro RNA involvement.
- Polyglandular diseases.
For the factors involved in the development of Hashimoto's thyroiditis, please click here.
References
- ↑ Ajjan RA, Weetman AP (2015). "The Pathogenesis of Hashimoto's Thyroiditis: Further Developments in our Understanding". Horm. Metab. Res. 47 (10): 702–10. doi:10.1055/s-0035-1548832. PMID 26361257.