Zollinger-Ellison syndrome causes: Difference between revisions
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The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref> | The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref> | ||
==Causes== | ==Causes== | ||
The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref> | |||
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| '''Causes of Hypergastrinemia''' <ref name="pmid21806955">{{cite journal| author=Metz DC| title=Diagnosis of the Zollinger–Ellison syndrome. | journal=Clin Gastroenterol Hepatol | year= 2012 | volume= 10 | issue= 2 | pages= 126-30 | pmid=21806955 | doi=10.1016/j.cgh.2011.07.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21806955 }} </ref> | |||
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|'''Appropriate hypergastrinemia''' | |'''Appropriate hypergastrinemia''' | ||
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Revision as of 16:07, 20 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 (MEN1).[1]
Causes
The cause of Zollinger-Ellison syndrome has not been identified. However, 25 to 30 percent of gastrinomas, which can cause Zollinger-Ellison syndrome, are caused by multiple endocrine neoplasia type 1 (MEN1).[1]
| Causes of Hypergastrinemia [2] |
| Appropriate hypergastrinemia |
| Atrophic gastritis with or without pernicious anemia |
| Antisecretory therapy (PPIs or high-dose histamine H2-receptor antagonist) |
| Chronic renal failure |
| H pylori pangastritis |
| Vagotomy |
| Inappropriate hypergastrinemia |
| ZES (sporadic or associated with MEN-1) |
| Antral-predominant H pylori infection |
| Retained-antrum syndrome |
| Gastric-outlet obstruction |
| Small-bowel resection |
| Spurious hypergastrinemia |
| Nonfasting patient |
| Inaccurate assay |
References
- ↑ 1.0 1.1 National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes
- ↑ Metz DC (2012). "Diagnosis of the Zollinger–Ellison syndrome". Clin Gastroenterol Hepatol. 10 (2): 126–30. doi:10.1016/j.cgh.2011.07.012. PMID 21806955.