Hashimoto's thyroiditis other diagnostic studies: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
The histological analysis in Hashimoto's thyroiditis may show inflammatory cell infiltration and | The histological analysis in Hashimoto's thyroiditis may show [[inflammatory]] cell infiltration and Hurthle cells. [[FNA|Fine needle aspiration cytology]] helps to differentiate between the [[benign]] and [[malignant]] [[nodules]]. <ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref> | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Fine needle aspiration cytology=== | ===Fine needle aspiration cytology=== | ||
[[Needle aspiration biopsy|Fine needle aspiration]] is usually done under ultrasound guidance and the sample is sent for [[cytology]]. It helps to differentiate benign thyroid nodules from the malignant lesions. | [[Needle aspiration biopsy|Fine needle aspiration]] is usually done under [[ultrasound]] guidance and the sample is sent for [[cytology]]. It helps to differentiate [[benign]] [[thyroid]] [[nodules]] from the [[malignant]] lesions. | ||
===Gross Pathology=== | ===Gross Pathology=== | ||
*The gland is usually diffusely enlarged, firm, and slightly lobular. The capsule is intact, and the cut surface is light-tan and has a slight lobular pattern. | *The gland is usually diffusely enlarged, firm, and slightly [[lobular]]. The capsule is intact, and the cut surface is light-tan and has a slight [[lobular]] pattern. | ||
*At autopsy, significant [[subarachnoid hemorrhage]] from the ruptured [[berry aneurysm]] was documented. In addition, the [[thyroid gland]] was mildly enlarged and firm. On cut section, the tissue was slightly pale. | *At autopsy, significant [[subarachnoid hemorrhage]] from the ruptured [[berry aneurysm]] was documented. In addition, the [[thyroid gland]] was mildly enlarged and firm. On cut section, the tissue was slightly pale. | ||
| Line 21: | Line 21: | ||
===Microscopic Pathology=== | ===Microscopic Pathology=== | ||
Microscopically there is massive infiltration of the thyroid gland by [[lymphocytes]] and [[Plasma cell|plasma cells]]. Germinal centers can often be seen in the gland. Thyroid follicles are usually absent and the few remaining follicles are devoid of colloid. | Microscopically there is massive infiltration of the [[thyroid gland]] by [[lymphocytes]] and [[Plasma cell|plasma cells]]. [[Germinal centers]] can often be seen in the [[gland]]. [[Thyroid]] follicles are usually absent and the few remaining follicles are devoid of [[colloid]]. | ||
[http://www.peir.net Images courtesy of Professor Peter Anderson DVM Ph.D. and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] | [http://www.peir.net Images courtesy of Professor Peter Anderson DVM Ph.D. and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] | ||
Revision as of 17:37, 1 September 2017
|
Hashimoto's thyroiditis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Hashimoto's thyroiditis other diagnostic studies On the Web |
|
American Roentgen Ray Society Images of Hashimoto's thyroiditis other diagnostic studies |
|
Hashimoto's thyroiditis other diagnostic studies in the news |
|
Risk calculators and risk factors for Hashimoto's thyroiditis other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The histological analysis in Hashimoto's thyroiditis may show inflammatory cell infiltration and Hurthle cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules. [1][2]
Other Diagnostic Studies
Fine needle aspiration cytology
Fine needle aspiration is usually done under ultrasound guidance and the sample is sent for cytology. It helps to differentiate benign thyroid nodules from the malignant lesions.
Gross Pathology
- The gland is usually diffusely enlarged, firm, and slightly lobular. The capsule is intact, and the cut surface is light-tan and has a slight lobular pattern.
- At autopsy, significant subarachnoid hemorrhage from the ruptured berry aneurysm was documented. In addition, the thyroid gland was mildly enlarged and firm. On cut section, the tissue was slightly pale.
Microscopic Pathology
Microscopically there is massive infiltration of the thyroid gland by lymphocytes and plasma cells. Germinal centers can often be seen in the gland. Thyroid follicles are usually absent and the few remaining follicles are devoid of colloid.
References
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ "Thyroiditis — NEJM".