Hypoglycemia historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
In 1922, | In 1922, hypoglycemia was first discovered by James Collip when he was working on purifying [[insulin]]. Collip discovered that by injection of a large dose of [[insulin]] into a rabbit, the rabbit developed a coma and died. | ||
==Historical Perspective<ref name="pmid12446492">{{cite journal| author=Rosenfeld L| title=Insulin: discovery and controversy. | journal=Clin Chem | year= 2002 | volume= 48 | issue= 12 | pages= 2270-88 | pmid=12446492 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12446492 }}</ref>== | ==Historical Perspective<ref name="pmid12446492">{{cite journal| author=Rosenfeld L| title=Insulin: discovery and controversy. | journal=Clin Chem | year= 2002 | volume= 48 | issue= 12 | pages= 2270-88 | pmid=12446492 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12446492 }}</ref>== | ||
* In 1869, Paul Langerhans | * In 1869, Paul Langerhans was the first who discovered a collection of cells within the [[pancreas]]. He called it [[islets of Langerhans]]. | ||
* In 1901''',''' Eugene Opie | * In 1901''',''' Eugene Opie was the first who discovered that destruction of [[Islet cell|islet cells]] results in [[diabetes mellitus]]. | ||
* In 1921, | * In 1921, Frederick Banting and Charles Best, 2 young orthopedic surgeons were the first who discovered [[insulin]] in the [[Pancreas|pancreatic]] extracts of dogs. With help of James B. Collip and J.J.R. Macleod, They have developed [[insulin]] for human treatment. Nobel Prize was awarded to Banting and Macleod for this discovery. | ||
* In 1922, Hypoglycemia was first discovered by James Collip when he was working on purifying insulin. He injected insulin into a rabbit and realized the reduction in blood glucose levels. Collip discovered that injection of a large dose of insulin, the rabbit got into a coma and died. | * In 1922, Hypoglycemia was first discovered by James Collip when he was working on purifying [[insulin]]. He injected [[insulin]] into a rabbit and realized the reduction in blood glucose levels. Collip discovered that injection of a large dose of [[insulin]], the rabbit got into a coma and died. | ||
* Hypoglycemia is a Greek word means under-sweet blood. | * Hypoglycemia is a Greek word means under-sweet blood. | ||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 15:44, 23 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
In 1922, hypoglycemia was first discovered by James Collip when he was working on purifying insulin. Collip discovered that by injection of a large dose of insulin into a rabbit, the rabbit developed a coma and died.
Historical Perspective[1]
- In 1869, Paul Langerhans was the first who discovered a collection of cells within the pancreas. He called it islets of Langerhans.
- In 1901, Eugene Opie was the first who discovered that destruction of islet cells results in diabetes mellitus.
- In 1921, Frederick Banting and Charles Best, 2 young orthopedic surgeons were the first who discovered insulin in the pancreatic extracts of dogs. With help of James B. Collip and J.J.R. Macleod, They have developed insulin for human treatment. Nobel Prize was awarded to Banting and Macleod for this discovery.
- In 1922, Hypoglycemia was first discovered by James Collip when he was working on purifying insulin. He injected insulin into a rabbit and realized the reduction in blood glucose levels. Collip discovered that injection of a large dose of insulin, the rabbit got into a coma and died.
- Hypoglycemia is a Greek word means under-sweet blood.
References
- ↑ Rosenfeld L (2002). "Insulin: discovery and controversy". Clin Chem. 48 (12): 2270–88. PMID 12446492.