21-hydroxylase deficiency classification: Difference between revisions
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==Classification== | ==Classification== | ||
21-hydroxylase deficiency my be classified by clinical manifestations in to two forms: | 21-hydroxylase deficiency my be classified by clinical manifestations in to two forms: | ||
*Classical form, most severe form of 21-hydroxylase deficiency, presents during the [[neonatal]] period and early infancy. The classic form can be classified in to two subtypes based on [[aldosterone]] status: | *Classical form, most severe form of 21-hydroxylase deficiency, presents during the [[neonatal]] period and early [[infancy]]. The classic form can be classified in to two subtypes based on [[aldosterone]] status: | ||
**Classic salt wasting, [[aldosterone]] deficient. | **Classic salt wasting, [[aldosterone]] deficient. | ||
**Classic non-salt wasting, normal [[aldosterone]]. | **Classic non-salt wasting, normal [[aldosterone]]. | ||
Revision as of 19:58, 16 August 2017
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21-hydroxylase deficiency Microchapters |
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Differentiating 21-Hydroxylase Deficiency from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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21-hydroxylase deficiency classification On the Web |
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American Roentgen Ray Society Images of 21-hydroxylase deficiency classification |
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Risk calculators and risk factors for 21-hydroxylase deficiency classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Mehrian Jafarizade, M.D [2]
Overview
21-hydroxylase deficiency may be classified into two subtypes based on severity and time of onset: classic and non-classic forms. Classic form includes two subtypes salt-wasting and non-salt wasting 21-hydroxylase deficiency.
Classification
21-hydroxylase deficiency my be classified by clinical manifestations in to two forms:
- Classical form, most severe form of 21-hydroxylase deficiency, presents during the neonatal period and early infancy. The classic form can be classified in to two subtypes based on aldosterone status:
- Classic salt wasting, aldosterone deficient.
- Classic non-salt wasting, normal aldosterone.
- Non-classic form or late-onset 21-hydroxylase deficiency, presents later during the adolescence period.[1][2]
References
- ↑ White PC, Speiser PW (2000). "Congenital adrenal hyperplasia due to 21-hydroxylase deficiency". Endocr. Rev. 21 (3): 245–91. doi:10.1210/edrv.21.3.0398. PMID 10857554.
- ↑ Speiser PW, Azziz R, Baskin LS, Ghizzoni L, Hensle TW, Merke DP, Meyer-Bahlburg HF, Miller WL, Montori VM, Oberfield SE, Ritzen M, White PC (2010). "Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline". J. Clin. Endocrinol. Metab. 95 (9): 4133–60. doi:10.1210/jc.2009-2631. PMC 2936060. PMID 20823466.