Osteoporosis classification: Difference between revisions
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* The main established classification system for osteoporosis is based on bone marrow density (BMD) in patients. The patients would be classified upon the site and method of measurements; also the used equipment and reference group of people may play roles. Finally, the major value using for classification of osteoporosis is T-score. T-score would be defined as "patient measured BMD value minus the reference BMD value (sex-matched and preferably for youth) divided the reference SD (sex-matched and preferably for youth)".<ref name="pmid11341335">{{cite journal |vauthors=Lu Y, Genant HK, Shepherd J, Zhao S, Mathur A, Fuerst TP, Cummings SR |title=Classification of osteoporosis based on bone mineral densities |journal=J. Bone Miner. Res. |volume=16 |issue=5 |pages=901–10 |year=2001 |pmid=11341335 |doi=10.1359/jbmr.2001.16.5.901 |url=}}</ref> | * The main established classification system for osteoporosis is based on bone marrow density (BMD) in patients. The patients would be classified upon the site and method of measurements; also the used equipment and reference group of people may play roles. Finally, the major value using for classification of osteoporosis is T-score. T-score would be defined as "patient measured BMD value minus the reference BMD value (sex-matched and preferably for youth) divided the reference SD (sex-matched and preferably for youth)".<ref name="pmid11341335">{{cite journal |vauthors=Lu Y, Genant HK, Shepherd J, Zhao S, Mathur A, Fuerst TP, Cummings SR |title=Classification of osteoporosis based on bone mineral densities |journal=J. Bone Miner. Res. |volume=16 |issue=5 |pages=901–10 |year=2001 |pmid=11341335 |doi=10.1359/jbmr.2001.16.5.901 |url=}}</ref> | ||
* The common classification of osteoporosis upon BMD measured T-score is as following: | * The common classification of osteoporosis upon BMD measured T-score is as following: | ||
** | *# T-score less than -1 and more than -2.5 assumes as osteopenia | ||
*# T-score equal to or less than -2.5 assumes as osteoporosis | |||
*# T-score equal to or less than -2.5 with history of fracture assumes as severe osteoporosis | |||
* Lu and colleagues have found that pure using of T-score and comparing to reference normative data aged 20-29 years, as world health organization (WHO) criteria, is very inconsistent. Compared to other classification systems, it is better to standardize the normative data, maybe referring to older people; and also complex the findings of multiple sites BMD measures, in order to obtain a better classification systam.<ref name="pmid11341335">{{cite journal |vauthors=Lu Y, Genant HK, Shepherd J, Zhao S, Mathur A, Fuerst TP, Cummings SR |title=Classification of osteoporosis based on bone mineral densities |journal=J. Bone Miner. Res. |volume=16 |issue=5 |pages=901–10 |year=2001 |pmid=11341335 |doi=10.1359/jbmr.2001.16.5.901 |url=}}</ref> | * Lu and colleagues have found that pure using of T-score and comparing to reference normative data aged 20-29 years, as world health organization (WHO) criteria, is very inconsistent. Compared to other classification systems, it is better to standardize the normative data, maybe referring to older people; and also complex the findings of multiple sites BMD measures, in order to obtain a better classification systam.<ref name="pmid11341335">{{cite journal |vauthors=Lu Y, Genant HK, Shepherd J, Zhao S, Mathur A, Fuerst TP, Cummings SR |title=Classification of osteoporosis based on bone mineral densities |journal=J. Bone Miner. Res. |volume=16 |issue=5 |pages=901–10 |year=2001 |pmid=11341335 |doi=10.1359/jbmr.2001.16.5.901 |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
- The main established classification system for osteoporosis is based on bone marrow density (BMD) in patients. The patients would be classified upon the site and method of measurements; also the used equipment and reference group of people may play roles. Finally, the major value using for classification of osteoporosis is T-score. T-score would be defined as "patient measured BMD value minus the reference BMD value (sex-matched and preferably for youth) divided the reference SD (sex-matched and preferably for youth)".[1]
- The common classification of osteoporosis upon BMD measured T-score is as following:
- T-score less than -1 and more than -2.5 assumes as osteopenia
- T-score equal to or less than -2.5 assumes as osteoporosis
- T-score equal to or less than -2.5 with history of fracture assumes as severe osteoporosis
- Lu and colleagues have found that pure using of T-score and comparing to reference normative data aged 20-29 years, as world health organization (WHO) criteria, is very inconsistent. Compared to other classification systems, it is better to standardize the normative data, maybe referring to older people; and also complex the findings of multiple sites BMD measures, in order to obtain a better classification systam.[1]