Zollinger-Ellison syndrome epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
The incidence of [[gastrinoma]], which can cause Zollinger-Ellison syndrome, is approximately 0.05-0.2 per 100,000 individuals worldwide. About 25 to 30 percent of gastrinomas are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).<ref name="NIDDK">National Institute of Diabetes and Digestive and Kidney Diseases.http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/zollinger-ellison-syndrome/Pages/facts.aspx#causes</ref>
The incidence of [[gastrinoma]], which can cause Zollinger-Ellison syndrome, is approximately 0.05-0.2 per 100,000 individuals worldwide. About 25 to 30 percent of gastrinomas are caused by  multiple endocrine neoplasia type 1 ([[MEN1]]).


==Epidemiology and Demographics==
==Epidemiology and Demographics==

Revision as of 15:21, 1 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

The incidence of gastrinoma, which can cause Zollinger-Ellison syndrome, is approximately 0.05-0.2 per 100,000 individuals worldwide. About 25 to 30 percent of gastrinomas are caused by multiple endocrine neoplasia type 1 (MEN1).

Epidemiology and Demographics

Incidence

  • The incidence of gastrinoma, which can cause Zollinger-Ellison syndrome, is approximately 0.5-2 persons per 100,000 individuals worldwide.[1]

Age

  • Zollinger-Ellison syndrome is a disease that tends to affect the middle-aged adult population (20-50 years of age).[2]

Gender

  • Males are more commonly affected with Zollinger-Ellison syndrome than females.[2]

References

  1. Jensen RT, Cadiot G, Brandi ML, de Herder WW, Kaltsas G, Komminoth P; et al. (2012). "ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes". Neuroendocrinology. 95 (2): 98–119. doi:10.1159/000335591. PMC 3701449. PMID 22261919.
  2. 2.0 2.1 Berna MJ, Hoffmann KM, Serrano J, Gibril F, Jensen RT (2006). "Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature". Medicine (Baltimore). 85 (6): 295–330. doi:10.1097/01.md.0000236956.74128.76. PMID 17108778.

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